Recent items - Diabetologia
Conditional ablation of Gsk-3beta in islet beta cells results in expanded mass and resistance to fat feeding-induced diabetes in mice.
10/09/2010 01:17
Related Articles Conditional ablation of Gsk-3beta in islet beta cells results in expanded mass and resistance to fat feeding-induced diabetes in mice. Diabetologia. 2010 Sep 7; Authors: Liu Y, Tanabe K, Baronnier D, Patel S, Woodgett J, Cras-Méneur C, Permutt MA AIMS/HYPOTHESIS: Glycogen synthase kinase 3beta (GSK-3beta) is an enzyme that is suppressed by insulin and when elevated results in insulin resistance in skeletal muscle and diabetes. Its role in bet [...]
10/09/2010 01:17
Related Articles Conditional ablation of Gsk-3beta in islet beta cells results in expanded mass and resistance to fat feeding-induced diabetes in mice. Diabetologia. 2010 Sep 7; Authors: Liu Y, Tanabe K, Baronnier D, Patel S, Woodgett J, Cras-Méneur C, Permutt MA AIMS/HYPOTHESIS: Glycogen synthase kinase 3beta (GSK-3beta) is an enzyme that is suppressed by insulin and when elevated results in insulin resistance in skeletal muscle and diabetes. Its role in bet [...]
Association of glycaemia with lipids in adults with type 1 diabetes: modification by dyslipidaemia medication.
10/09/2010 01:17
Related Articles Association of glycaemia with lipids in adults with type 1 diabetes: modification by dyslipidaemia medication. Diabetologia. 2010 Sep 4; Authors: Maahs DM, Ogden LG, Dabelea D, Snell-Bergeon JK, Daniels SR, Hamman RF, Rewers M AIMS/HYPOTHESIS: Hyperglycaemia and dyslipidaemia are common metabolic abnormalities in adults with type 1 diabetes and both increase cardiovascular disease (CVD) risk. The hypothesis of this study was that change in HbA [...]
10/09/2010 01:17
Related Articles Association of glycaemia with lipids in adults with type 1 diabetes: modification by dyslipidaemia medication. Diabetologia. 2010 Sep 4; Authors: Maahs DM, Ogden LG, Dabelea D, Snell-Bergeon JK, Daniels SR, Hamman RF, Rewers M AIMS/HYPOTHESIS: Hyperglycaemia and dyslipidaemia are common metabolic abnormalities in adults with type 1 diabetes and both increase cardiovascular disease (CVD) risk. The hypothesis of this study was that change in HbA [...]
Screening for gestational diabetes mellitus: cost-utility of different screening strategies based on a woman's individual risk of disease.
05/09/2010 02:49
Related Articles Screening for gestational diabetes mellitus: cost-utility of different screening strategies based on a woman's individual risk of disease. Diabetologia. 2010 Aug 31; Authors: Round JA, Jacklin P, Fraser RB, Hughes RG, Mugglestone MA, Holt RI AIMS/HYPOTHESIS: The cost-effectiveness of eight strategies for screening for gestational diabetes (including no screening) was estimated with respect to the level of individual patient risk. METHODS: Cost- [...]
05/09/2010 02:49
Related Articles Screening for gestational diabetes mellitus: cost-utility of different screening strategies based on a woman's individual risk of disease. Diabetologia. 2010 Aug 31; Authors: Round JA, Jacklin P, Fraser RB, Hughes RG, Mugglestone MA, Holt RI AIMS/HYPOTHESIS: The cost-effectiveness of eight strategies for screening for gestational diabetes (including no screening) was estimated with respect to the level of individual patient risk. METHODS: Cost- [...]
Ageing brain abnormalities in young obese patients with type 2 diabetes: a cause for concern.
31/08/2010 14:58
Related Articles Ageing brain abnormalities in young obese patients with type 2 diabetes: a cause for concern. Diabetologia. 2010 Aug 30; Authors: Nolan JJ PMID: 20803339 [PubMed - as supplied by publisher]
31/08/2010 14:58
Related Articles Ageing brain abnormalities in young obese patients with type 2 diabetes: a cause for concern. Diabetologia. 2010 Aug 30; Authors: Nolan JJ PMID: 20803339 [PubMed - as supplied by publisher]
Biomedical risk factors for decreased cognitive functioning in type 1 diabetes: an 18 year follow-up of the Diabetes Control and Complications Trial (DCCT) cohort.
31/08/2010 14:58
Related Articles Biomedical risk factors for decreased cognitive functioning in type 1 diabetes: an 18 year follow-up of the Diabetes Control and Complications Trial (DCCT) cohort. Diabetologia. 2010 Aug 29; Authors: Jacobson AM, Ryan CM, Cleary PA, Waberski BH, Weinger K, Musen G, Dahms W, AIMS/HYPOTHESIS: In patients with type 1 diabetes, there has been concern about the effects of recurrent hypoglycaemia and chronic hyperglycaemia on cognitive function. Be [...]
31/08/2010 14:58
Related Articles Biomedical risk factors for decreased cognitive functioning in type 1 diabetes: an 18 year follow-up of the Diabetes Control and Complications Trial (DCCT) cohort. Diabetologia. 2010 Aug 29; Authors: Jacobson AM, Ryan CM, Cleary PA, Waberski BH, Weinger K, Musen G, Dahms W, AIMS/HYPOTHESIS: In patients with type 1 diabetes, there has been concern about the effects of recurrent hypoglycaemia and chronic hyperglycaemia on cognitive function. Be [...]
From authority recommendations to fact-sheets-a future for guidelines.
31/08/2010 14:58
Related Articles From authority recommendations to fact-sheets-a future for guidelines. Diabetologia. 2010 Aug 29; Authors: Mühlhauser I ADA/EASD recommendations and diabetes expert consensus statements are not evidence-based. Reform of guideline development is urgently needed. Overriding governance and composition of the guideline committee is a key problem. Methodologists without important conflicts of interest should lead the development process and have pr [...]
31/08/2010 14:58
Related Articles From authority recommendations to fact-sheets-a future for guidelines. Diabetologia. 2010 Aug 29; Authors: Mühlhauser I ADA/EASD recommendations and diabetes expert consensus statements are not evidence-based. Reform of guideline development is urgently needed. Overriding governance and composition of the guideline committee is a key problem. Methodologists without important conflicts of interest should lead the development process and have pr [...]
Cholesterol toxicity in pancreatic islets from LDL receptor-deficient mice. Reply to: de Souza JC, de Oliveira CAM, Carneiro EM et al. [letter].
28/08/2010 02:25
Related Articles Cholesterol toxicity in pancreatic islets from LDL receptor-deficient mice. Reply to: de Souza JC, de Oliveira CAM, Carneiro EM et al. [letter]. Diabetologia. 2010 Aug 26; Authors: Kruit JK, Brunham LR, Verchere CB, Hayden MR PMID: 20740272 [PubMed - as supplied by publisher]
28/08/2010 02:25
Related Articles Cholesterol toxicity in pancreatic islets from LDL receptor-deficient mice. Reply to: de Souza JC, de Oliveira CAM, Carneiro EM et al. [letter]. Diabetologia. 2010 Aug 26; Authors: Kruit JK, Brunham LR, Verchere CB, Hayden MR PMID: 20740272 [PubMed - as supplied by publisher]
Health behaviours, socioeconomic status and diabetes incidence: the Australian Diabetes Obesity and Lifestyle Study (AusDiab).
28/08/2010 02:25
Related Articles Health behaviours, socioeconomic status and diabetes incidence: the Australian Diabetes Obesity and Lifestyle Study (AusDiab). Diabetologia. 2010 Aug 26; Authors: Williams ED, Tapp RJ, Magliano DJ, Shaw JE, Zimmet PZ, Oldenburg BF AIMS/HYPOTHESIS: To identify the impact of socioeconomic status on incident impaired glucose metabolism and type 2 diabetes and to investigate the mediating role of health behaviours on this relationship using nationa [...]
28/08/2010 02:25
Related Articles Health behaviours, socioeconomic status and diabetes incidence: the Australian Diabetes Obesity and Lifestyle Study (AusDiab). Diabetologia. 2010 Aug 26; Authors: Williams ED, Tapp RJ, Magliano DJ, Shaw JE, Zimmet PZ, Oldenburg BF AIMS/HYPOTHESIS: To identify the impact of socioeconomic status on incident impaired glucose metabolism and type 2 diabetes and to investigate the mediating role of health behaviours on this relationship using nationa [...]
Guidelines: we'll always need them, we sometimes dislike them, and we have to make them better.
25/08/2010 19:29
Related Articles Guidelines: we'll always need them, we sometimes dislike them, and we have to make them better. Diabetologia. 2010 Aug 25; Authors: Kahn R PMID: 20734022 [PubMed - as supplied by publisher]
25/08/2010 19:29
Related Articles Guidelines: we'll always need them, we sometimes dislike them, and we have to make them better. Diabetologia. 2010 Aug 25; Authors: Kahn R PMID: 20734022 [PubMed - as supplied by publisher]
Hypoglycaemia following gastric bypass surgery-diabetes remission in the extreme?
24/08/2010 17:00
Related Articles Hypoglycaemia following gastric bypass surgery-diabetes remission in the extreme? Diabetologia. 2010 Aug 21; Authors: Patti ME, Goldfine AB Postprandial hypoglycaemia is increasingly recognised as a complication of gastric bypass surgery. While post-bypass hypoglycaemia is often responsive to dietary modification, a subset of individuals develop life-threatening neuroglycopenia, with loss of consciousness, seizures and motor vehicle accidents. [...]
24/08/2010 17:00
Related Articles Hypoglycaemia following gastric bypass surgery-diabetes remission in the extreme? Diabetologia. 2010 Aug 21; Authors: Patti ME, Goldfine AB Postprandial hypoglycaemia is increasingly recognised as a complication of gastric bypass surgery. While post-bypass hypoglycaemia is often responsive to dietary modification, a subset of individuals develop life-threatening neuroglycopenia, with loss of consciousness, seizures and motor vehicle accidents. [...]
Posthumous Caesarean section in women with type 1 diabetes mellitus: two cases at one hospital in northern India.
22/08/2010 17:59
Related Articles Posthumous Caesarean section in women with type 1 diabetes mellitus: two cases at one hospital in northern India. Diabetologia. 2010 Aug 20; Authors: Kalra B, Kalra S, Chhabra B PMID: 20725714 [PubMed - as supplied by publisher]
22/08/2010 17:59
Related Articles Posthumous Caesarean section in women with type 1 diabetes mellitus: two cases at one hospital in northern India. Diabetologia. 2010 Aug 20; Authors: Kalra B, Kalra S, Chhabra B PMID: 20725714 [PubMed - as supplied by publisher]
Abstracts of the EASD, Stockholm 2010 : held in Messe Wien, Vienna, Austria on 1 October 2009.
20/08/2010 21:39
Related Articles Abstracts of the EASD, Stockholm 2010 : held in Messe Wien, Vienna, Austria on 1 October 2009. Diabetologia. 2010 Sep;53(Suppl 1):1-556 Authors: PMID: 20690007 [PubMed - in process]
20/08/2010 21:39
Related Articles Abstracts of the EASD, Stockholm 2010 : held in Messe Wien, Vienna, Austria on 1 October 2009. Diabetologia. 2010 Sep;53(Suppl 1):1-556 Authors: PMID: 20690007 [PubMed - in process]
Genetic variants affecting incretin sensitivity and incretin secretion.
19/08/2010 01:51
Related Articles Genetic variants affecting incretin sensitivity and incretin secretion. Diabetologia. 2010 Aug 17; Authors: Müssig K, Staiger H, Machicao F, Häring HU, Fritsche A Recent genome-wide association studies identified several novel risk genes for type 2 diabetes. The majority of these type 2 diabetes risk variants confer impaired pancreatic beta cell function. Though the molecular mechanisms by which common genetic variation within these loci affe [...]
19/08/2010 01:51
Related Articles Genetic variants affecting incretin sensitivity and incretin secretion. Diabetologia. 2010 Aug 17; Authors: Müssig K, Staiger H, Machicao F, Häring HU, Fritsche A Recent genome-wide association studies identified several novel risk genes for type 2 diabetes. The majority of these type 2 diabetes risk variants confer impaired pancreatic beta cell function. Though the molecular mechanisms by which common genetic variation within these loci affe [...]
A polymorphism in the gene encoding carnosinase (CNDP1) as a predictor of mortality and progression from nephropathy to end-stage renal disease in type 1 diabetes mellitus.
17/08/2010 13:35
Related Articles A polymorphism in the gene encoding carnosinase (CNDP1) as a predictor of mortality and progression from nephropathy to end-stage renal disease in type 1 diabetes mellitus. Diabetologia. 2010 Aug 14; Authors: Alkhalaf A, Bakker SJ, Bilo HJ, Gans RO, Navis GJ, Postmus D, Forsblom C, Groop PH, Vionnet N, Hadjadj S, Marre M, Parving HH, Rossing P, Tarnow L AIMS/HYPOTHESIS: Homozygosity for a five leucine repeat (5L-5L) in the carnosinase gene (CND [...]
17/08/2010 13:35
Related Articles A polymorphism in the gene encoding carnosinase (CNDP1) as a predictor of mortality and progression from nephropathy to end-stage renal disease in type 1 diabetes mellitus. Diabetologia. 2010 Aug 14; Authors: Alkhalaf A, Bakker SJ, Bilo HJ, Gans RO, Navis GJ, Postmus D, Forsblom C, Groop PH, Vionnet N, Hadjadj S, Marre M, Parving HH, Rossing P, Tarnow L AIMS/HYPOTHESIS: Homozygosity for a five leucine repeat (5L-5L) in the carnosinase gene (CND [...]
Dysglycaemia and the risk of acute myocardial infarction in multiple ethnic groups: an analysis of 15,780 patients from the INTERHEART study.
17/08/2010 13:35
Related Articles Dysglycaemia and the risk of acute myocardial infarction in multiple ethnic groups: an analysis of 15,780 patients from the INTERHEART study. Diabetologia. 2010 Aug 14; Authors: Gerstein HC, Islam S, Anand S, Almahmeed W, Damasceno A, Dans A, Lang CC, Luna MA, McQueen M, Rangarajan S, Rosengren A, Wang X, Yusuf S AIMS/HYPOTHESIS: Although diabetes is an established risk factor for myocardial infarction (MI), disease control may vary. HbA(1c) is [...]
17/08/2010 13:35
Related Articles Dysglycaemia and the risk of acute myocardial infarction in multiple ethnic groups: an analysis of 15,780 patients from the INTERHEART study. Diabetologia. 2010 Aug 14; Authors: Gerstein HC, Islam S, Anand S, Almahmeed W, Damasceno A, Dans A, Lang CC, Luna MA, McQueen M, Rangarajan S, Rosengren A, Wang X, Yusuf S AIMS/HYPOTHESIS: Although diabetes is an established risk factor for myocardial infarction (MI), disease control may vary. HbA(1c) is [...]
Type 2 diabetes mellitus as a risk factor for the onset of depression: a systematic review and meta-analysis.
17/08/2010 13:35
Related Articles Type 2 diabetes mellitus as a risk factor for the onset of depression: a systematic review and meta-analysis. Diabetologia. 2010 Aug 14; Authors: Nouwen A, Winkley K, Twisk J, Lloyd CE, Peyrot M, Ismail K, Pouwer F, AIMS/HYPOTHESIS: An earlier meta-analysis showed that diabetes is a risk factor for the development and/or recurrence of depression. Yet whether this risk is different for studies using questionnaires than for those relying on dia [...]
17/08/2010 13:35
Related Articles Type 2 diabetes mellitus as a risk factor for the onset of depression: a systematic review and meta-analysis. Diabetologia. 2010 Aug 14; Authors: Nouwen A, Winkley K, Twisk J, Lloyd CE, Peyrot M, Ismail K, Pouwer F, AIMS/HYPOTHESIS: An earlier meta-analysis showed that diabetes is a risk factor for the development and/or recurrence of depression. Yet whether this risk is different for studies using questionnaires than for those relying on dia [...]
Sensor-augmented pump therapy from the diagnosis of childhood type 1 diabetes: results of the Paediatric Onset Study (ONSET) after 12 months of treatment.
17/08/2010 13:35
Related Articles Sensor-augmented pump therapy from the diagnosis of childhood type 1 diabetes: results of the Paediatric Onset Study (ONSET) after 12 months of treatment. Diabetologia. 2010 Aug 14; Authors: Kordonouri O, Pankowska E, Rami B, Kapellen T, Coutant R, Hartmann R, Lange K, Knip M, Danne T AIMS/HYPOTHESIS: The value of managing children with type 1 diabetes using a combination of insulin pump and continuous glucose monitoring starting from diagnosis [...]
17/08/2010 13:35
Related Articles Sensor-augmented pump therapy from the diagnosis of childhood type 1 diabetes: results of the Paediatric Onset Study (ONSET) after 12 months of treatment. Diabetologia. 2010 Aug 14; Authors: Kordonouri O, Pankowska E, Rami B, Kapellen T, Coutant R, Hartmann R, Lange K, Knip M, Danne T AIMS/HYPOTHESIS: The value of managing children with type 1 diabetes using a combination of insulin pump and continuous glucose monitoring starting from diagnosis [...]
Multidrug therapy in a patient with Rabson-Mendenhall syndrome.
17/08/2010 13:35
Related Articles Multidrug therapy in a patient with Rabson-Mendenhall syndrome. Diabetologia. 2010 Aug 14; Authors: Moreira RO, Zagury RL, Nascimento TS, Zagury L PMID: 20711714 [PubMed - as supplied by publisher]
17/08/2010 13:35
Related Articles Multidrug therapy in a patient with Rabson-Mendenhall syndrome. Diabetologia. 2010 Aug 14; Authors: Moreira RO, Zagury RL, Nascimento TS, Zagury L PMID: 20711714 [PubMed - as supplied by publisher]
Leisure-time physical activity and type 2 diabetes during a 28 year follow-up in twins.
14/08/2010 12:31
Related Articles Leisure-time physical activity and type 2 diabetes during a 28 year follow-up in twins. Diabetologia. 2010 Aug 13; Authors: Waller K, Kaprio J, Lehtovirta M, Silventoinen K, Koskenvuo M, Kujala UM AIMS/HYPOTHESIS: The study aimed to investigate whether baseline physical activity protects against the occurrence of type 2 diabetes during a 28 year follow-up, after controlling for childhood environment and genetic predisposition. METHODS: At basel [...]
14/08/2010 12:31
Related Articles Leisure-time physical activity and type 2 diabetes during a 28 year follow-up in twins. Diabetologia. 2010 Aug 13; Authors: Waller K, Kaprio J, Lehtovirta M, Silventoinen K, Koskenvuo M, Kujala UM AIMS/HYPOTHESIS: The study aimed to investigate whether baseline physical activity protects against the occurrence of type 2 diabetes during a 28 year follow-up, after controlling for childhood environment and genetic predisposition. METHODS: At basel [...]
Expression analysis of loci associated with type 2 diabetes in human tissues.
14/08/2010 02:47
Related Articles Expression analysis of loci associated with type 2 diabetes in human tissues. Diabetologia. 2010 Aug 12; Authors: Cotsapas C, Prokunina-Olsson L, Welch C, Saxena R, Weaver C, Usher N, Guiducci C, Bonakdar S, Turner N, Lacroix B, Hall JL AIMS/HYPOTHESIS: Genetic mapping has identified over 20 loci contributing to genetic risk of type 2 diabetes. The next step is to identify the genes and mechanisms regulating the contributions of genetic risk to [...]
14/08/2010 02:47
Related Articles Expression analysis of loci associated with type 2 diabetes in human tissues. Diabetologia. 2010 Aug 12; Authors: Cotsapas C, Prokunina-Olsson L, Welch C, Saxena R, Weaver C, Usher N, Guiducci C, Bonakdar S, Turner N, Lacroix B, Hall JL AIMS/HYPOTHESIS: Genetic mapping has identified over 20 loci contributing to genetic risk of type 2 diabetes. The next step is to identify the genes and mechanisms regulating the contributions of genetic risk to [...]
Day/night variations of high-molecular-weight adiponectin and lipocalin-2 in healthy men studied under fed and fasted conditions.
14/08/2010 02:47
Related Articles Day/night variations of high-molecular-weight adiponectin and lipocalin-2 in healthy men studied under fed and fasted conditions. Diabetologia. 2010 Aug 12; Authors: Scheer FA, Chan JL, Fargnoli J, Chamberland J, Arampatzi K, Shea SA, Blackburn GL, Mantzoros CS AIMS/HYPOTHESIS: Adiponectin and lipocalin-2 are adipocyte-derived plasma proteins that have been proposed to have opposite effects on insulin sensitivity. Given the epidemiological, phy [...]
14/08/2010 02:47
Related Articles Day/night variations of high-molecular-weight adiponectin and lipocalin-2 in healthy men studied under fed and fasted conditions. Diabetologia. 2010 Aug 12; Authors: Scheer FA, Chan JL, Fargnoli J, Chamberland J, Arampatzi K, Shea SA, Blackburn GL, Mantzoros CS AIMS/HYPOTHESIS: Adiponectin and lipocalin-2 are adipocyte-derived plasma proteins that have been proposed to have opposite effects on insulin sensitivity. Given the epidemiological, phy [...]
Oral disease and subsequent cardiovascular disease in people with type 2 diabetes: a prospective cohort study based on the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified-Release Controlled Evaluation (ADVANCE) trial.
12/08/2010 16:11
Oral disease and subsequent cardiovascular disease in people with type 2 diabetes: a prospective cohort study based on the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified-Release Controlled Evaluation (ADVANCE) trial. Diabetologia. 2010 Aug 11; Authors: Li Q, Chalmers J, Czernichow S, Neal B, Taylor BA, Zoungas S, Poulter N, Woodward M, Patel A, de Galan B, Batty GD, AIMS/HYPOTHESIS: While there are plausible biological mechanisms li [...]
12/08/2010 16:11
Oral disease and subsequent cardiovascular disease in people with type 2 diabetes: a prospective cohort study based on the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified-Release Controlled Evaluation (ADVANCE) trial. Diabetologia. 2010 Aug 11; Authors: Li Q, Chalmers J, Czernichow S, Neal B, Taylor BA, Zoungas S, Poulter N, Woodward M, Patel A, de Galan B, Batty GD, AIMS/HYPOTHESIS: While there are plausible biological mechanisms li [...]
Healthcare costs in patients with diabetes mellitus and comorbid mental disorders-a systematic review.
12/08/2010 16:11
Healthcare costs in patients with diabetes mellitus and comorbid mental disorders-a systematic review. Diabetologia. 2010 Aug 11; Authors: Hutter N, Schnurr A, Baumeister H AIMS/HYPOTHESIS: We systematically reviewed the impact of comorbid mental disorders on healthcare costs in persons with diabetes. METHOD: We conducted a comprehensive search for studies investigating adult persons (>/=18 years old) with diabetes mellitus. All studies that allowed compari [...]
12/08/2010 16:11
Healthcare costs in patients with diabetes mellitus and comorbid mental disorders-a systematic review. Diabetologia. 2010 Aug 11; Authors: Hutter N, Schnurr A, Baumeister H AIMS/HYPOTHESIS: We systematically reviewed the impact of comorbid mental disorders on healthcare costs in persons with diabetes. METHOD: We conducted a comprehensive search for studies investigating adult persons (>/=18 years old) with diabetes mellitus. All studies that allowed compari [...]
Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance.
12/08/2010 08:55
Related Articles Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance. Diabetologia. 2010 Aug 11; Authors: Matthews VB, Allen TL, Risis S, Chan MH, Henstridge DC, Watson N, Zaffino LA, Babb JR, Boon J, Meikle PJ, Jowett JB, Watt MJ, Jansson JO, Bruce CR, Febbraio MA AIMS/HYPOTHESIS: The role of IL-6 in the development of obesity and hepatic insulin resistance is unclear and still the subject of controversy. We aimed to deter [...]
12/08/2010 08:55
Related Articles Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance. Diabetologia. 2010 Aug 11; Authors: Matthews VB, Allen TL, Risis S, Chan MH, Henstridge DC, Watson N, Zaffino LA, Babb JR, Boon J, Meikle PJ, Jowett JB, Watt MJ, Jansson JO, Bruce CR, Febbraio MA AIMS/HYPOTHESIS: The role of IL-6 in the development of obesity and hepatic insulin resistance is unclear and still the subject of controversy. We aimed to deter [...]
HbA(1c) as predictor of all-cause mortality in individuals at high risk of diabetes with normal glucose tolerance, identified by screening: a follow-up study of the Anglo-Danish-Dutch Study of Intensive Treatment in People with Screen-Detected Diabetes in
12/08/2010 08:55
Related Articles HbA(1c) as predictor of all-cause mortality in individuals at high risk of diabetes with normal glucose tolerance, identified by screening: a follow-up study of the Anglo-Danish-Dutch Study of Intensive Treatment in People with Screen-Detected Diabetes in Primary Care (ADDITION), Denmark. Diabetologia. 2010 Aug 11; Authors: Skriver MV, Borch-Johnsen K, Lauritzen T, Sandbaek A AIMS/HYPOTHESIS: Stepwise screening for type 2 diabetes will not only [...]
12/08/2010 08:55
Related Articles HbA(1c) as predictor of all-cause mortality in individuals at high risk of diabetes with normal glucose tolerance, identified by screening: a follow-up study of the Anglo-Danish-Dutch Study of Intensive Treatment in People with Screen-Detected Diabetes in Primary Care (ADDITION), Denmark. Diabetologia. 2010 Aug 11; Authors: Skriver MV, Borch-Johnsen K, Lauritzen T, Sandbaek A AIMS/HYPOTHESIS: Stepwise screening for type 2 diabetes will not only [...]
A mutation in KCNJ11 causing human hyperinsulinism (Y12X) results in a glucose-intolerant phenotype in the mouse.
10/08/2010 12:55
A mutation in KCNJ11 causing human hyperinsulinism (Y12X) results in a glucose-intolerant phenotype in the mouse. Diabetologia. 2010 Aug 8; Authors: Hugill A, Shimomura K, Ashcroft FM, Cox RD AIMS/HYPOTHESIS: We identified a mouse with a point mutation (Y12STOP) in the Kcnj11 subunit of the K(ATP) channel. This point mutation is identical to that found in a patient with congenital hyperinsulinism of infancy (HI). We aimed to characterise the phenotype arising [...]
10/08/2010 12:55
A mutation in KCNJ11 causing human hyperinsulinism (Y12X) results in a glucose-intolerant phenotype in the mouse. Diabetologia. 2010 Aug 8; Authors: Hugill A, Shimomura K, Ashcroft FM, Cox RD AIMS/HYPOTHESIS: We identified a mouse with a point mutation (Y12STOP) in the Kcnj11 subunit of the K(ATP) channel. This point mutation is identical to that found in a patient with congenital hyperinsulinism of infancy (HI). We aimed to characterise the phenotype arising [...]
Cholesterol toxicity in pancreatic islets from LDL receptor-deficient mice.
10/08/2010 12:55
Cholesterol toxicity in pancreatic islets from LDL receptor-deficient mice. Diabetologia. 2010 Aug 6; Authors: de Souza JC, de Oliveira CA, Carneiro EM, Boschero AC, de Oliveira HC PMID: 20694455 [PubMed - as supplied by publisher]
10/08/2010 12:55
Cholesterol toxicity in pancreatic islets from LDL receptor-deficient mice. Diabetologia. 2010 Aug 6; Authors: de Souza JC, de Oliveira CA, Carneiro EM, Boschero AC, de Oliveira HC PMID: 20694455 [PubMed - as supplied by publisher]
Intensified glucose lowering in type 2 diabetes: time for a reappraisal.
06/08/2010 13:47
Intensified glucose lowering in type 2 diabetes: time for a reappraisal. Diabetologia. 2010 Aug 5; Authors: Yudkin JS, Richter B, Gale EA PMID: 20686748 [PubMed - as supplied by publisher]
06/08/2010 13:47
Intensified glucose lowering in type 2 diabetes: time for a reappraisal. Diabetologia. 2010 Aug 5; Authors: Yudkin JS, Richter B, Gale EA PMID: 20686748 [PubMed - as supplied by publisher]
Transgenic expression of haem oxygenase-1 in pancreatic beta cells protects non-obese mice used as a model of diabetes from autoimmune destruction and prolongs graft survival following islet transplantation.
05/08/2010 13:39
Transgenic expression of haem oxygenase-1 in pancreatic beta cells protects non-obese mice used as a model of diabetes from autoimmune destruction and prolongs graft survival following islet transplantation. Diabetologia. 2010 Aug 5; Authors: Huang SH, Chu CH, Yu JC, Chuang WC, Lin GJ, Chen PL, Chou FC, Chau LY, Sytwu HK AIMS/HYPOTHESIS: Haem oxygenase 1 (HO-1) has strong anti-apoptotic, anti-inflammatory and antioxidative effects that help protect cells again [...]
05/08/2010 13:39
Transgenic expression of haem oxygenase-1 in pancreatic beta cells protects non-obese mice used as a model of diabetes from autoimmune destruction and prolongs graft survival following islet transplantation. Diabetologia. 2010 Aug 5; Authors: Huang SH, Chu CH, Yu JC, Chuang WC, Lin GJ, Chen PL, Chou FC, Chau LY, Sytwu HK AIMS/HYPOTHESIS: Haem oxygenase 1 (HO-1) has strong anti-apoptotic, anti-inflammatory and antioxidative effects that help protect cells again [...]
Insulin secretion and impaired glucose tolerance. Reply to Mari A, Ferrannini E [letter].
04/08/2010 13:51
Insulin secretion and impaired glucose tolerance. Reply to Mari A, Ferrannini E [letter]. Diabetologia. 2010 Aug 3; Authors: Jenkins AB, Campbell LV PMID: 20680242 [PubMed - as supplied by publisher]
04/08/2010 13:51
Insulin secretion and impaired glucose tolerance. Reply to Mari A, Ferrannini E [letter]. Diabetologia. 2010 Aug 3; Authors: Jenkins AB, Campbell LV PMID: 20680242 [PubMed - as supplied by publisher]
Further refinement of the critical minimal genetic region for the imprinting disorder 6q24 transient neonatal diabetes.
31/07/2010 05:07
Related Articles Further refinement of the critical minimal genetic region for the imprinting disorder 6q24 transient neonatal diabetes. Diabetologia. 2010 Jul 30; Authors: Docherty LE, Poole RL, Mattocks CJ, Lehmann A, Temple IK, Mackay DJ AIMS/HYPOTHESIS: Transient neonatal diabetes (TND) is associated with overexpression of genes within a critical region on 6q24. This study aims to refine the boundaries of this region to reduce the number of potential candi [...]
31/07/2010 05:07
Related Articles Further refinement of the critical minimal genetic region for the imprinting disorder 6q24 transient neonatal diabetes. Diabetologia. 2010 Jul 30; Authors: Docherty LE, Poole RL, Mattocks CJ, Lehmann A, Temple IK, Mackay DJ AIMS/HYPOTHESIS: Transient neonatal diabetes (TND) is associated with overexpression of genes within a critical region on 6q24. This study aims to refine the boundaries of this region to reduce the number of potential candi [...]
Estimated glomerular filtration rate and albuminuria are independent predictors of cardiovascular events and death in type 2 diabetes mellitus: the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study.
31/07/2010 05:07
Related Articles Estimated glomerular filtration rate and albuminuria are independent predictors of cardiovascular events and death in type 2 diabetes mellitus: the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. Diabetologia. 2010 Jul 30; Authors: Drury PL, Ting R, Zannino D, Ehnholm C, Flack J, Whiting M, Fassett R, Ansquer JC, Dixon P, Davis TM, Pardy C, Colman P, Keech A AIMS/HYPOTHESIS: We investigated effects of renal function and [...]
31/07/2010 05:07
Related Articles Estimated glomerular filtration rate and albuminuria are independent predictors of cardiovascular events and death in type 2 diabetes mellitus: the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. Diabetologia. 2010 Jul 30; Authors: Drury PL, Ting R, Zannino D, Ehnholm C, Flack J, Whiting M, Fassett R, Ansquer JC, Dixon P, Davis TM, Pardy C, Colman P, Keech A AIMS/HYPOTHESIS: We investigated effects of renal function and [...]
Preliminary evidence for brain complications in obese adolescents with type 2 diabetes mellitus.
31/07/2010 05:07
Related Articles Preliminary evidence for brain complications in obese adolescents with type 2 diabetes mellitus. Diabetologia. 2010 Jul 30; Authors: Yau PL, Javier DC, Ryan CM, Tsui WH, Ardekani BA, Ten S, Convit A AIMS/HYPOTHESIS: Central nervous system abnormalities, including cognitive and brain impairments, have been documented in adults with type 2 diabetes who also have multiple co-morbid disorders that could contribute to these observations. Assessing [...]
31/07/2010 05:07
Related Articles Preliminary evidence for brain complications in obese adolescents with type 2 diabetes mellitus. Diabetologia. 2010 Jul 30; Authors: Yau PL, Javier DC, Ryan CM, Tsui WH, Ardekani BA, Ten S, Convit A AIMS/HYPOTHESIS: Central nervous system abnormalities, including cognitive and brain impairments, have been documented in adults with type 2 diabetes who also have multiple co-morbid disorders that could contribute to these observations. Assessing [...]
In the absence of renal disease, 20 year mortality risk in type 1 diabetes is comparable to that of the general population: a report from the Pittsburgh Epidemiology of Diabetes Complications Study.
29/07/2010 12:39
In the absence of renal disease, 20 year mortality risk in type 1 diabetes is comparable to that of the general population: a report from the Pittsburgh Epidemiology of Diabetes Complications Study. Diabetologia. 2010 Jul 28; Authors: Orchard TJ, Secrest AM, Miller RG, Costacou T AIMS/HYPOTHESIS: The FinnDiane Study has reported that mortality in type 1 diabetes is not increased over a 7 year follow-up in the absence of renal disease (RD). Using the Pittsburgh [...]
29/07/2010 12:39
In the absence of renal disease, 20 year mortality risk in type 1 diabetes is comparable to that of the general population: a report from the Pittsburgh Epidemiology of Diabetes Complications Study. Diabetologia. 2010 Jul 28; Authors: Orchard TJ, Secrest AM, Miller RG, Costacou T AIMS/HYPOTHESIS: The FinnDiane Study has reported that mortality in type 1 diabetes is not increased over a 7 year follow-up in the absence of renal disease (RD). Using the Pittsburgh [...]