Recent items - Current opinion in allergy and clinical immunology
Current world literature.
26/08/2010 12:49
Current world literature. Curr Opin Allergy Clin Immunol. 2010 Oct;10(5):511-4 Authors: PMID: 20736734 [PubMed - in process]
26/08/2010 12:49
Current world literature. Curr Opin Allergy Clin Immunol. 2010 Oct;10(5):511-4 Authors: PMID: 20736734 [PubMed - in process]
The cellular orchestra in skin allergy; are differences to lung and nose relevant?
26/08/2010 12:49
The cellular orchestra in skin allergy; are differences to lung and nose relevant? Curr Opin Allergy Clin Immunol. 2010 Oct;10(5):443-51 Authors: Akdis M PURPOSE OF REVIEW: It has been a long lasting question that although a similar peripheral allergen-specific immune response has been observed, why some patients show only atopic dermatitis, rhinitis and asthma alone or their combinations. The answer resides in the propensity of resident tissue cells and local [...]
26/08/2010 12:49
The cellular orchestra in skin allergy; are differences to lung and nose relevant? Curr Opin Allergy Clin Immunol. 2010 Oct;10(5):443-51 Authors: Akdis M PURPOSE OF REVIEW: It has been a long lasting question that although a similar peripheral allergen-specific immune response has been observed, why some patients show only atopic dermatitis, rhinitis and asthma alone or their combinations. The answer resides in the propensity of resident tissue cells and local [...]
Next generation genetics in allergy.
26/08/2010 12:49
Next generation genetics in allergy. Curr Opin Allergy Clin Immunol. 2010 Oct;10(5):407 Authors: Kabesch M PMID: 20736731 [PubMed - in process]
26/08/2010 12:49
Next generation genetics in allergy. Curr Opin Allergy Clin Immunol. 2010 Oct;10(5):407 Authors: Kabesch M PMID: 20736731 [PubMed - in process]
Editorial introductions.
26/08/2010 12:49
Editorial introductions. Curr Opin Allergy Clin Immunol. 2010 Oct;10(5):vii-ix Authors: PMID: 20736730 [PubMed - in process]
26/08/2010 12:49
Editorial introductions. Curr Opin Allergy Clin Immunol. 2010 Oct;10(5):vii-ix Authors: PMID: 20736730 [PubMed - in process]
Genome-wide association studies on IgE regulation: are genetics of IgE also genetics of atopic disease?
26/08/2010 12:49
Genome-wide association studies on IgE regulation: are genetics of IgE also genetics of atopic disease? Curr Opin Allergy Clin Immunol. 2010 Oct;10(5):408-17 Authors: Weidinger S, Baurecht H, Naumann A, Novak N PURPOSE OF REVIEW: Total IgE levels are considered a useful endophenotype for studying the genetics of atopic diseases. However, the role and significance of genetic factors influencing IgE regulation for atopic diseases as endpoints is unclear. RECENT [...]
26/08/2010 12:49
Genome-wide association studies on IgE regulation: are genetics of IgE also genetics of atopic disease? Curr Opin Allergy Clin Immunol. 2010 Oct;10(5):408-17 Authors: Weidinger S, Baurecht H, Naumann A, Novak N PURPOSE OF REVIEW: Total IgE levels are considered a useful endophenotype for studying the genetics of atopic diseases. However, the role and significance of genetic factors influencing IgE regulation for atopic diseases as endpoints is unclear. RECENT [...]
The ocular surface in thyroid diseases.
21/08/2010 21:39
Related Articles The ocular surface in thyroid diseases. Curr Opin Allergy Clin Immunol. 2010 Aug 18; Authors: Versura P, Campos EC PURPOSE OF REVIEW: The purpose of the present review is to describe recent insights into the pathomechanism of ocular surface impairment in the course of thyroid dysfunctions. The review focuses in particular on Graves' ophthalmopathy as the majority of the literature is published on this topic. RECENT FINDINGS: Mechanical factors [...]
21/08/2010 21:39
Related Articles The ocular surface in thyroid diseases. Curr Opin Allergy Clin Immunol. 2010 Aug 18; Authors: Versura P, Campos EC PURPOSE OF REVIEW: The purpose of the present review is to describe recent insights into the pathomechanism of ocular surface impairment in the course of thyroid dysfunctions. The review focuses in particular on Graves' ophthalmopathy as the majority of the literature is published on this topic. RECENT FINDINGS: Mechanical factors [...]
Genomewide association studies in allergy and the influence of ethnicity.
21/08/2010 21:39
Related Articles Genomewide association studies in allergy and the influence of ethnicity. Curr Opin Allergy Clin Immunol. 2010 Aug 18; Authors: Barnes KC PURPOSE OF REVIEW: Asthma and allergic diseases are common and disproportionately affect racial and ethnic minorities. Large-scale research efforts and the expense committed to multiple genomewide association studies (GWAS) have led to the identification of numerous susceptibility loci for the allergic diseas [...]
21/08/2010 21:39
Related Articles Genomewide association studies in allergy and the influence of ethnicity. Curr Opin Allergy Clin Immunol. 2010 Aug 18; Authors: Barnes KC PURPOSE OF REVIEW: Asthma and allergic diseases are common and disproportionately affect racial and ethnic minorities. Large-scale research efforts and the expense committed to multiple genomewide association studies (GWAS) have led to the identification of numerous susceptibility loci for the allergic diseas [...]
Unraveling the complex genetic underpinnings of asthma and allergic disorders.
21/08/2010 21:39
Related Articles Unraveling the complex genetic underpinnings of asthma and allergic disorders. Curr Opin Allergy Clin Immunol. 2010 Aug 18; Authors: Swarr DT, Hakonarson H PURPOSE OF REVIEW: Asthma and other allergic diseases are complex genetic disorders that result from interactions between multiple genes and environmental factors. In this review, we summarize findings from candidate gene analyses, discuss the recent success of genome-wide association (GWA) [...]
21/08/2010 21:39
Related Articles Unraveling the complex genetic underpinnings of asthma and allergic disorders. Curr Opin Allergy Clin Immunol. 2010 Aug 18; Authors: Swarr DT, Hakonarson H PURPOSE OF REVIEW: Asthma and other allergic diseases are complex genetic disorders that result from interactions between multiple genes and environmental factors. In this review, we summarize findings from candidate gene analyses, discuss the recent success of genome-wide association (GWA) [...]
Treatment of seasonal allergic conjunctivitis with ophthalmic corticosteroids: in search of the perfect ocular corticosteroids in the treatment of allergic conjunctivitis.
20/08/2010 14:27
Related Articles Treatment of seasonal allergic conjunctivitis with ophthalmic corticosteroids: in search of the perfect ocular corticosteroids in the treatment of allergic conjunctivitis. Curr Opin Allergy Clin Immunol. 2010 Aug 17; Authors: Bielory BP, Perez VL, Bielory L PURPOSE OF REVIEW: Corticosteroids are an effective short-term treatment option for seasonal allergic conjunctivitis (SAC). Their use has been limited due to their side effects and has led t [...]
20/08/2010 14:27
Related Articles Treatment of seasonal allergic conjunctivitis with ophthalmic corticosteroids: in search of the perfect ocular corticosteroids in the treatment of allergic conjunctivitis. Curr Opin Allergy Clin Immunol. 2010 Aug 17; Authors: Bielory BP, Perez VL, Bielory L PURPOSE OF REVIEW: Corticosteroids are an effective short-term treatment option for seasonal allergic conjunctivitis (SAC). Their use has been limited due to their side effects and has led t [...]
Atopic keratoconjunctivitis and atopic dermatitis.
20/08/2010 14:27
Related Articles Atopic keratoconjunctivitis and atopic dermatitis. Curr Opin Allergy Clin Immunol. 2010 Aug 17; Authors: Guglielmetti S, Dart JK, Calder V PURPOSE OF REVIEW: This review will focus on the diagnostic features of atopic keratoconjunctivitis (AKC), its relationship to atopic dermatitis, the immunopathogenesis, and therapy, and will include strategies used for the management of severe disease unresponsive to conventional therapy. RECENT FINDINGS: R [...]
20/08/2010 14:27
Related Articles Atopic keratoconjunctivitis and atopic dermatitis. Curr Opin Allergy Clin Immunol. 2010 Aug 17; Authors: Guglielmetti S, Dart JK, Calder V PURPOSE OF REVIEW: This review will focus on the diagnostic features of atopic keratoconjunctivitis (AKC), its relationship to atopic dermatitis, the immunopathogenesis, and therapy, and will include strategies used for the management of severe disease unresponsive to conventional therapy. RECENT FINDINGS: R [...]
Innate immunity, allergy and atopic dermatitis.
20/08/2010 14:27
Related Articles Innate immunity, allergy and atopic dermatitis. Curr Opin Allergy Clin Immunol. 2010 Aug 17; Authors: Niebuhr M, Werfel T PURPOSE OF REVIEW: We review here the recent discoveries in innate immunity that shed light on the pathophysiology of atopic dermatitis. RECENT FINDINGS: The mechanisms that promote the enhanced susceptibility to cutaneous infections in atopic dermatitis are complex interactions among several factors. They include skin barri [...]
20/08/2010 14:27
Related Articles Innate immunity, allergy and atopic dermatitis. Curr Opin Allergy Clin Immunol. 2010 Aug 17; Authors: Niebuhr M, Werfel T PURPOSE OF REVIEW: We review here the recent discoveries in innate immunity that shed light on the pathophysiology of atopic dermatitis. RECENT FINDINGS: The mechanisms that promote the enhanced susceptibility to cutaneous infections in atopic dermatitis are complex interactions among several factors. They include skin barri [...]
Neurogenic inflammation of the ocular surface.
14/08/2010 15:19
Related Articles Neurogenic inflammation of the ocular surface. Curr Opin Allergy Clin Immunol. 2010 Aug 11; Authors: Mantelli F, Micera A, Sacchetti M, Bonini S PURPOSE OF REVIEW: The purpose of the present review is to describe the involvement of neurogenic inflammation in ocular surface diseases and to outline recent advances in understanding the complex interaction of neuromediators and inflammatory cells in the conjunctiva. RECENT FINDINGS: Evidence indica [...]
14/08/2010 15:19
Related Articles Neurogenic inflammation of the ocular surface. Curr Opin Allergy Clin Immunol. 2010 Aug 11; Authors: Mantelli F, Micera A, Sacchetti M, Bonini S PURPOSE OF REVIEW: The purpose of the present review is to describe the involvement of neurogenic inflammation in ocular surface diseases and to outline recent advances in understanding the complex interaction of neuromediators and inflammatory cells in the conjunctiva. RECENT FINDINGS: Evidence indica [...]
Update in drug allergy: novel drugs with novel reaction patterns.
14/08/2010 15:19
Related Articles Update in drug allergy: novel drugs with novel reaction patterns. Curr Opin Allergy Clin Immunol. 2010 Aug 11; Authors: Rubio M, Bousquet PJ, Demoly P PURPOSE OF REVIEW: In the last years, many novel drugs have been introduced, generating new patterns of drug hypersensitivity. There are also novel clinical and biologic techniques that have enabled us to understand the mechanisms and diagnosis of reactions to old used drugs. This review summariz [...]
14/08/2010 15:19
Related Articles Update in drug allergy: novel drugs with novel reaction patterns. Curr Opin Allergy Clin Immunol. 2010 Aug 11; Authors: Rubio M, Bousquet PJ, Demoly P PURPOSE OF REVIEW: In the last years, many novel drugs have been introduced, generating new patterns of drug hypersensitivity. There are also novel clinical and biologic techniques that have enabled us to understand the mechanisms and diagnosis of reactions to old used drugs. This review summariz [...]
Genome-wide approaches to the etiology of eczema.
14/08/2010 15:19
Related Articles Genome-wide approaches to the etiology of eczema. Curr Opin Allergy Clin Immunol. 2010 Aug 11; Authors: Esparza-Gordillo J, Marenholz I, Lee YA PURPOSE OF REVIEW: The present review summarizes the new discoveries in the genetics of eczema, focusing on the results from the recently published first genome-wide association study. RECENT FINDINGS: The first genome-wide association study for eczema included 10 000 individuals and provided strong evi [...]
14/08/2010 15:19
Related Articles Genome-wide approaches to the etiology of eczema. Curr Opin Allergy Clin Immunol. 2010 Aug 11; Authors: Esparza-Gordillo J, Marenholz I, Lee YA PURPOSE OF REVIEW: The present review summarizes the new discoveries in the genetics of eczema, focusing on the results from the recently published first genome-wide association study. RECENT FINDINGS: The first genome-wide association study for eczema included 10 000 individuals and provided strong evi [...]
Pathogenic role of Demodex mites in blepharitis.
07/08/2010 14:47
Pathogenic role of Demodex mites in blepharitis. Curr Opin Allergy Clin Immunol. 2010 Aug 4; Authors: Liu J, Sheha H, Tseng SC PURPOSE OF REVIEW: To summarize the key literature and our research experience regarding Demodex infestation as a potential cause of ocular inflammatory diseases with a special emphasis on Demodex blepharitis. RECENT FINDINGS: Two distinct Demodex species have been confirmed as a cause of blepharitis: Demodex folliculorum can cause ant [...]
07/08/2010 14:47
Pathogenic role of Demodex mites in blepharitis. Curr Opin Allergy Clin Immunol. 2010 Aug 4; Authors: Liu J, Sheha H, Tseng SC PURPOSE OF REVIEW: To summarize the key literature and our research experience regarding Demodex infestation as a potential cause of ocular inflammatory diseases with a special emphasis on Demodex blepharitis. RECENT FINDINGS: Two distinct Demodex species have been confirmed as a cause of blepharitis: Demodex folliculorum can cause ant [...]
High-risk corneal allografts and why they lose their immune privilege.
07/08/2010 14:47
High-risk corneal allografts and why they lose their immune privilege. Curr Opin Allergy Clin Immunol. 2010 Aug 4; Authors: Niederkorn JY PURPOSE OF REVIEW: Corneal allografts are routinely performed without HLA typing or systemic immunosuppressive drugs. However, certain conditions create high risks for immune rejection. This review discusses recent insights into the mechanisms that rob the corneal allograft of its immune privilege. RECENT FINDINGS: Studies i [...]
07/08/2010 14:47
High-risk corneal allografts and why they lose their immune privilege. Curr Opin Allergy Clin Immunol. 2010 Aug 4; Authors: Niederkorn JY PURPOSE OF REVIEW: Corneal allografts are routinely performed without HLA typing or systemic immunosuppressive drugs. However, certain conditions create high risks for immune rejection. This review discusses recent insights into the mechanisms that rob the corneal allograft of its immune privilege. RECENT FINDINGS: Studies i [...]
Keratinocytes in allergic skin diseases.
07/08/2010 14:47
Keratinocytes in allergic skin diseases. Curr Opin Allergy Clin Immunol. 2010 Aug 4; Authors: Albanesi C PURPOSE OF REVIEW: The aim of the review is to provide up-to-date information on the multiple roles of epidermal keratinocytes in the immune reactions associated with allergic contact dermatitis and atopic dermatitis skin diseases. RECENT FINDINGS: In the last two decades, it has become clear that keratinocytes are highly active immunological cells, with ma [...]
07/08/2010 14:47
Keratinocytes in allergic skin diseases. Curr Opin Allergy Clin Immunol. 2010 Aug 4; Authors: Albanesi C PURPOSE OF REVIEW: The aim of the review is to provide up-to-date information on the multiple roles of epidermal keratinocytes in the immune reactions associated with allergic contact dermatitis and atopic dermatitis skin diseases. RECENT FINDINGS: In the last two decades, it has become clear that keratinocytes are highly active immunological cells, with ma [...]