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Recent items - Multiple Sclerosis Papers in the Pubmed Database

multiple sclerosis; +18 new citations
06/09/2010 08:25
18 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: multiple sclerosis These pubmed results were generated on 2010/09/06PubMed, a service of the National Library of Medicine, includes over 15 million citations for biomedical articles back to the 1950's. These citations are from MEDLINE and additional life science journals. PubMed includes links to many sites providing full text articles and other related resource [...]
multiple sclerosis; +29 new citations
03/09/2010 14:37
29 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: multiple sclerosis These pubmed results were generated on 2010/09/03PubMed, a service of the National Library of Medicine, includes over 15 million citations for biomedical articles back to the 1950's. These citations are from MEDLINE and additional life science journals. PubMed includes links to many sites providing full text articles and other related resource [...]
Novel method for measurement of fatigue in multiple sclerosis: Real-Time Digital Fatigue Score.
01/09/2010 00:09
Related Articles Novel method for measurement of fatigue in multiple sclerosis: Real-Time Digital Fatigue Score. J Rehabil Res Dev. 2010;47(5):477-84 Authors: Kim E, Lovera J, Schaben L, Melara J, Bourdette D, Whitham R The study's objective was to develop a real-time measurement for fatigue and to evaluate whether it is an effective clinical trial outcome measure compared with the Fatigue Severity Scale (FSS) and the Modified Fatigue Impact Scale (MFIS). Forty [...]
Guest Editorial: Integrated multiple sclerosis care: New approaches and paradigm shifts.
01/09/2010 00:09
Related Articles Guest Editorial: Integrated multiple sclerosis care: New approaches and paradigm shifts. J Rehabil Res Dev. 2010;47(5):ix-xiv Authors: Wallin MT PMID: 20803384 [PubMed - in process]
Heterozygous X-linked adrenoleukodystrophy-associated myelopathy mimicking primary progressive multiple sclerosis.
01/09/2010 00:09
Related Articles Heterozygous X-linked adrenoleukodystrophy-associated myelopathy mimicking primary progressive multiple sclerosis. J Neurol. 2010 Aug 31; Authors: Di Filippo M, Luchetti E, Prontera P, Donti E, Floridi P, Di Gregorio M, Tambasco N, Sarchielli P, Calabresi P PMID: 20803344 [PubMed - as supplied by publisher]
Recurrent tumefactive demyelination without evidence of multiple sclerosis or brain tumour.
01/09/2010 00:09
Related Articles Recurrent tumefactive demyelination without evidence of multiple sclerosis or brain tumour. J Neurol. 2010 Aug 29; Authors: Häne A, Bargetzi M, Hewer E, Bruehlmeier M, Khamis A, Roelcke U PMID: 20803212 [PubMed - as supplied by publisher]
The Association of Keratoconus With Immune Disorders.
01/09/2010 00:09
Related Articles The Association of Keratoconus With Immune Disorders. Cornea. 2010 Aug 26; Authors: Nemet AY, Vinker S, Bahar I, Kaiserman I PURPOSE:: To evaluate the association between keratoconus (KC) and immune disorders (IDs). METHODS:: A retrospective observational case-control study of all the members in the Central District of Clalit Health Services in Israel who were diagnosed to have KC (years 2000-2007; n = 426) and 1704 age- and gender-matched cont [...]
Genetic variation influences glutamate concentrations in brains of patients with multiple sclerosis.
01/09/2010 00:09
Related Articles Genetic variation influences glutamate concentrations in brains of patients with multiple sclerosis. Brain. 2010 Sep;133(Pt 9):2603-11 Authors: Baranzini SE, Srinivasan R, Khankhanian P, Okuda DT, Nelson SJ, Matthews PM, Hauser SL, Oksenberg JR, Pelletier D Glutamate is the main excitatory neurotransmitter in the mammalian brain. Appropriate transmission of nerve impulses through glutamatergic synapses is required throughout the brain and forms [...]
How long can you keep working with benign multiple sclerosis?
01/09/2010 00:09
Related Articles How long can you keep working with benign multiple sclerosis? J Neurol Neurosurg Psychiatry. 2010 Aug 27; Authors: Glad SB, Nyland H, Aarseth JH, Riise T, Myhr KM Objective To study employment in benign multiple sclerosis (MS), the frequency of employment was analysed and the effect of early clinical and demographic factors on time to disability pension was evaluated in a population based MS cohort. The frequency of depression, cognitive functi [...]
TNF-{alpha} antagonists beyond approved indications: stories of success and prospects for the future.
01/09/2010 00:09
Related Articles TNF-{alpha} antagonists beyond approved indications: stories of success and prospects for the future. QJM. 2010 Aug 27; Authors: Karampetsou MP, Liossis SN, Sfikakis PP Tumour necrosis factor alpha (TNF-alpha) is a key molecule of the inflammatory response and data derived from studies in experimental animal models and humans suggest that TNF-alpha may be implicated in the pathogenesis of various autoimmune and non-infectious inflammatory condi [...]
Predicting Exercise Capacity Through Submaximal Fitness Tests in Persons With Multiple Sclerosis.
01/09/2010 00:09
Related Articles Predicting Exercise Capacity Through Submaximal Fitness Tests in Persons With Multiple Sclerosis. Arch Phys Med Rehabil. 2010 Sep;91(9):1410-1417 Authors: Kuspinar A, Andersen RE, Teng SY, Asano M, Mayo NE Kuspinar A, Andersen RE, Teng SY, Asano M, Mayo NE. Predicting exercise capacity through submaximal fitness tests in persons with multiple sclerosis. OBJECTIVE: To estimate, for persons with multiple sclerosis (MS), the extent to which peak o [...]
Protein profiling of Guillain-Barrè Syndrome cerebrospinal fluid by two dimensional electrophoresis and mass spectrometry.
01/09/2010 00:09
Related Articles Protein profiling of Guillain-Barrè Syndrome cerebrospinal fluid by two dimensional electrophoresis and mass spectrometry. Neurosci Lett. 2010 Aug 26; Authors: D'Aguanno S, Franciotta D, Lupisella S, Barassi A, Pieragostino D, Lugaresi A, Centonze D, D'Eril GM, Bernardini S, Federici G, Urbani A Protein profiling of cerebrospinal fluid in Guillain-Barrè Syndrome (GBS), an acute and immune-mediated disease affecting the peripheral nervous syst [...]
Common variation in the MOG gene influences transcript splicing in humans.
01/09/2010 00:09
Related Articles Common variation in the MOG gene influences transcript splicing in humans. J Neuroimmunol. 2010 Aug 26; Authors: Jensen CJ, Stankovich J, Butzkueven H, Oldfield BJ, Rubio JP Multiple sclerosis (MS) is a complex autoimmune disease characterised by demyelinating lesions in the central nervous system (CNS) and myelin oligodendrocyte glycoprotein (MOG), a CNS-restricted protein expressed on the outer cell membrane of oligodendrocytes, has been link [...]
Interventional endovascular management of chronic cerebrospinal venous insufficiency in patients with multiple sclerosis: a position statement by the society of interventional radiology, endorsed by the canadian interventional radiology association.
01/09/2010 00:09
Related Articles Interventional endovascular management of chronic cerebrospinal venous insufficiency in patients with multiple sclerosis: a position statement by the society of interventional radiology, endorsed by the canadian interventional radiology association. J Vasc Interv Radiol. 2010 Sep;21(9):1335-7 Authors: Vedantham S, Benenati JF, Kundu S, Black CM, Murphy KJ, Cardella JF PMID: 20800776 [PubMed - in process]
Enhanced suppressive function of regulatory T cells from patients with immune-mediated diseases following successful ex vivo expansion.
01/09/2010 00:09
Related Articles Enhanced suppressive function of regulatory T cells from patients with immune-mediated diseases following successful ex vivo expansion. Clin Immunol. 2010 Sep;136(3):329-37 Authors: Cao T, Wenzel SE, Faubion WA, Harriman G, Li L Recent studies and our current data demonstrated the deficits in the numbers and/or functions of the CD4(+)CD25(+)Foxp3(+) Treg cells in the patients with autoimmune diseases, indicating that restoration of Treg cells [...]
Multiple sclerosis: Putting a dampener on inflammation.
01/09/2010 00:09
Related Articles Multiple sclerosis: Putting a dampener on inflammation. Nat Rev Neurosci. 2010 Sep;11(9):610 Authors: Kingwell K PMID: 20803791 [PubMed - in process]
Manifestations of systemic sclerosis necessitate a holistic approach to patient care: a case report.
01/09/2010 00:09
Related Articles Manifestations of systemic sclerosis necessitate a holistic approach to patient care: a case report. Musculoskeletal Care. 2010 Sep;8(3):164-7 Authors: Moots RJ This case describes a young woman with manifestations of systemic sclerosis in multiple organ systems and her guidance through two successful pregnancies. This case emphasizes that patients with severe diseases are not just clinical cases; they each have unique needs and concerns beyond [...]
Antiviral immune response in patients with multiple sclerosis, healthy siblings and twins.
29/08/2010 04:21
Related Articles Antiviral immune response in patients with multiple sclerosis, healthy siblings and twins. Mult Scler. 2010 Aug 26; Authors: Ristori G, Mechelli R, Anderson J, Mengoni F, Sauzullo I, Annibali V, Cannoni S, Aloisi F, James JA, Salvetti M PMID: 20798134 [PubMed - as supplied by publisher]
Involvement of brain-derived neurotrophic factor (BDNF) in MP4-induced autoimmune encephalomyelitis.
29/08/2010 04:21
Related Articles Involvement of brain-derived neurotrophic factor (BDNF) in MP4-induced autoimmune encephalomyelitis. Clin Immunol. 2010 Aug 24; Authors: Javeri S, Rodi M, Tary-Lehmann M, Lehmann PV, Addicks K, Kuerten S The role of brain-derived neurotrophic factor (BDNF) in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE) is still unclear. Here we investigate the clinical course, CNS histopathology and peripheral antigen-specific immunit [...]
Combined exercise training reduces IFN-gamma and IL-17 levels in the plasma and the supernatant of peripheral blood mononuclear cells in women with multiple sclerosis.
29/08/2010 04:21
Related Articles Combined exercise training reduces IFN-gamma and IL-17 levels in the plasma and the supernatant of peripheral blood mononuclear cells in women with multiple sclerosis. Int Immunopharmacol. 2010 Aug 23; Authors: Golzari Z, Shabkhiz F, Soudi S, Kordi MR, Hashemi SM Multiple sclerosis (MS) is a chronic inflammatory demyelinating disorder in which lymphocytic infiltration mediated mainly by pro-inflammatory cytokines. In this study, we examined the [...]
Evaluation of change in fatigue, self-efficacy and health-related quality of life, after a group educational intervention programme for persons with neuromuscular diseases or multiple sclerosis: a pilot study.
29/08/2010 04:21
Related Articles Evaluation of change in fatigue, self-efficacy and health-related quality of life, after a group educational intervention programme for persons with neuromuscular diseases or multiple sclerosis: a pilot study. Disabil Rehabil. 2010 Aug 27; Authors: Boosman H, Visser-Meily JM, Meijer JW, Elsinga A, Post MW Purpose. An intervention for persons with neuromuscular diseases (NMD) or multiple sclerosis (MS) who experienced severe fatigue was develope [...]
Treatment options for multiple sclerosis: current and emerging therapies.
29/08/2010 04:21
Related Articles Treatment options for multiple sclerosis: current and emerging therapies. Pharmacotherapy. 2010 Sep;30(9):916-27 Authors: Gawronski KM, Rainka MM, Patel MJ, Gengo FM Abstract Multiple sclerosis is a chronic autoimmune disease affecting the central nervous system, more specifically, the myelin sheath covering of nerve fibers in the brain and spinal cord. This disease requires lifelong disease-modifying therapy, and all of the currently available [...]
Therapeutic approaches to multiple sclerosis: an update on failed, interrupted, or inconclusive trials of neuroprotective and alternative treatment strategies.
29/08/2010 04:21
Related Articles Therapeutic approaches to multiple sclerosis: an update on failed, interrupted, or inconclusive trials of neuroprotective and alternative treatment strategies. BioDrugs. 2010 Oct 1;24(5):317-30 Authors: Meuth SG, Bittner S, Ulzheimer JC, Kleinschnitz C, Kieseier BC, Wiendl H Currently approved multiple sclerosis (MS) therapeutics have a mainly anti-inflammatory mode of action. However, a number of promising clinical trials have been initiated t [...]
Oxygen cost of treadmill and over-ground walking in mildly disabled persons with multiple sclerosis.
29/08/2010 04:21
Related Articles Oxygen cost of treadmill and over-ground walking in mildly disabled persons with multiple sclerosis. Neurol Sci. 2010 Aug 27; Authors: Motl RW, Suh Y, Dlugonski D, Weikert M, Agiovlasitis S, Fernhall B, Goldman M Walking impairment is a ubiquitous feature of multiple sclerosis (MS) and the O(2) cost of walking might quantify this dysfunction in mild MS. This paper examined the difference in O(2) cost of walking between persons with MS who have [...]
Use of Physical Therapy Services Among Middle-Aged and Older Adults With Multiple Sclerosis.
29/08/2010 04:21
Related Articles Use of Physical Therapy Services Among Middle-Aged and Older Adults With Multiple Sclerosis. Phys Ther. 2010 Aug 26; Authors: Finlayson M, Plow M, Cho C Background There is limited understanding of the utilization of and perceived need for physical therapy services among middle-aged and older adults with multiple sclerosis (MS). The resulting knowledge gap compromises efforts for physical therapy service planning for this population. Objective [...]
A novel adaptive design strategy increases the efficiency of clinical trials in secondary progressive multiple sclerosis.
29/08/2010 04:21
Related Articles A novel adaptive design strategy increases the efficiency of clinical trials in secondary progressive multiple sclerosis. Mult Scler. 2010 Aug 26; Authors: Chataway J, Nicholas R, Todd S, Miller DH, Parsons N, Valdés-Márquez E, Stallard N, Friede T Background: Adaptive seamless designs (ASDs) have been proposed to test multiple candidate compounds using an interim decision point which allows potentially effective therapies to be taken into th [...]
Interaction between aging and neurodegeneration in amyotrophic lateral sclerosis.
28/08/2010 05:38
Related Articles Interaction between aging and neurodegeneration in amyotrophic lateral sclerosis. Neurobiol Aging. 2010 Aug 23; Authors: Tedeschi G, Trojsi F, Tessitore A, Corbo D, Sagnelli A, Paccone A, D'Ambrosio A, Piccirillo G, Cirillo M, Cirillo S, Monsurrò MR, Esposito F We assessed the spontaneous blood-oxygen-level-dependent signal fluctuations in the resting-state brain networks of amyotrophic lateral sclerosis patients and their relation to physiolo [...]
[Clinical, radiographic, prognostic and therapeutic aspects of demelinating disease with tumefactive demyelinating lesions.]
28/08/2010 05:38
Related Articles [Clinical, radiographic, prognostic and therapeutic aspects of demelinating disease with tumefactive demyelinating lesions.] Rev Neurol (Paris). 2010 Aug 23; Authors: Launay M, Lebrun C, Giordana E, Chanalet S, Thomas P BACKGROUND: Demyelinating diseases presenting with a tumefactive demyelinating lesion (TDL) raise questions about classification, diagnosis, prognosis, and treatment. Their long-term course is not well described in literature. P [...]
Late B Cell Depletion with a Human Anti-Human CD20 IgG1{kappa} Monoclonal Antibody Halts the Development of Experimental Autoimmune Encephalomyelitis in Marmosets.
28/08/2010 05:38
Related Articles Late B Cell Depletion with a Human Anti-Human CD20 IgG1{kappa} Monoclonal Antibody Halts the Development of Experimental Autoimmune Encephalomyelitis in Marmosets. J Immunol. 2010 Aug 25; Authors: Kap YS, van Driel N, Blezer E, Parren PW, Bleeker WK, Laman JD, Craigen JL, 't Hart BA Depletion of CD20(+) B cells has been related to reduced clinical activity in relapsing-remitting multiple sclerosis. The underlying mechanism is not understood, be [...]
Imaging distribution and frequency of cortical lesions in patients with multiple sclerosis.
28/08/2010 05:38
Related Articles Imaging distribution and frequency of cortical lesions in patients with multiple sclerosis. Neurology. 2010 Aug 25; Authors: Calabrese M, Battaglini M, Giorgio A, Atzori M, Bernardi V, Mattisi I, Gallo P, De Stefano N BACKGROUND: The presence of cortical lesions (CLs) and their topographic distribution in the brains of patients with multiple sclerosis (MS) have been clearly shown by recent histopathologic studies. CLs can also be assessed in vi [...]
Toward understanding cortical lesions in multiple sclerosis.
28/08/2010 05:38
Related Articles Toward understanding cortical lesions in multiple sclerosis. Neurology. 2010 Aug 25; Authors: Geurts JJ, Vrenken H PMID: 20739643 [PubMed - as supplied by publisher]
Detection of Epstein-Barr virus and B-cell follicles in the multiple sclerosis brain: what you find depends on how and where you look.
28/08/2010 05:38
Related Articles Detection of Epstein-Barr virus and B-cell follicles in the multiple sclerosis brain: what you find depends on how and where you look. Brain. 2010 Aug 25; Authors: Aloisi F, Serafini B, Magliozzi R, Howell OW, Reynolds R PMID: 20739348 [PubMed - as supplied by publisher]
Cytokine and chemokine profiles in neuromyelitis optica: significance of interleukin-6.
28/08/2010 05:38
Related Articles Cytokine and chemokine profiles in neuromyelitis optica: significance of interleukin-6. Mult Scler. 2010 Aug 25; Authors: Uzawa A, Mori M, Arai K, Sato Y, Hayakawa S, Masuda S, Taniguchi J, Kuwabara S Background: Neuromyelitis optica (NMO) is assumed to be immunologically distinct from multiple sclerosis (MS). Adequate studies about cytokines and chemokines in NMO have been lacking.Objective: To investigate the contribution of cytokines/chemoki [...]
Immunomodulatory effects of vitamin D on monocyte-derived dendritic cells in multiple sclerosis.
28/08/2010 05:38
Related Articles Immunomodulatory effects of vitamin D on monocyte-derived dendritic cells in multiple sclerosis. Mult Scler. 2010 Aug 25; Authors: Bartosik-Psujek H, Tabarkiewicz J, Pocinska K, Stelmasiak Z, Rolinski J In order to evaluate the effects of vitamin D3 on monocyte-derived dendritic cells (DCs) of relapsing-remitting multiple sclerosis patients, DCs differentiation and maturation were evaluated in vitro based on surface phenotypic changes. The expr [...]
Evaluation of the symbol digit modalities test (SDMT) and MS neuropsychological screening questionnaire (MSNQ) in natalizumab-treated MS patients over 48 weeks.
28/08/2010 05:38
Related Articles Evaluation of the symbol digit modalities test (SDMT) and MS neuropsychological screening questionnaire (MSNQ) in natalizumab-treated MS patients over 48 weeks. Mult Scler. 2010 Aug 25; Authors: Morrow S, O'Connor P, Polman C, Goodman A, Kappos L, Lublin F, Rudick R, Jurgensen S, Paes D, Forrestal F, Benedict R Background and Objectives: Brief cognitive tests to monitor cognitive impairment in patients with multiple sclerosis (MS) are needed.Me [...]
Spanish Neurology Society consensus document on the use of drugs in multiple sclerosis: escalating therapy.
28/08/2010 05:38
Related Articles Spanish Neurology Society consensus document on the use of drugs in multiple sclerosis: escalating therapy. Neurologia. 2010 Jul;25(6):378-390 Authors: García Merino A, Fernández O, Montalbán X, de Andrés C, Arbizu T INTRODUCTION: Treatment of multiple sclerosis has advanced considerably in the last few years, at the same time as its complexity has increased. The purpose of this consensus document is to provide specific recommendations and [...]
Common Genetic Variants of the Mitochondrial Trafficking System and Mitochondrial Uncoupling Proteins Affect the Development of Two Slowly Developing Demyelinating Disorders, Leukoaraiosis and Multiple Sclerosis.
28/08/2010 05:38
Related Articles Common Genetic Variants of the Mitochondrial Trafficking System and Mitochondrial Uncoupling Proteins Affect the Development of Two Slowly Developing Demyelinating Disorders, Leukoaraiosis and Multiple Sclerosis. Curr Med Chem. 2010 Aug 26; Authors: Szolnoki Z As the central energy source, the mitochondria are of great importance in the maintenance of the glia cells of the brain. It is presumed that mitochondrial energy production is affected n [...]
Polypropylene ankle foot orthoses to overcome drop-foot gait in central neurological patients: A mechanical and functional evaluation.
28/08/2010 05:38
Related Articles Polypropylene ankle foot orthoses to overcome drop-foot gait in central neurological patients: A mechanical and functional evaluation. Prosthet Orthot Int. 2010 Sep;34(3):293-304 Authors: Bregman DJ, De Groot V, Van Diggele P, Meulman H, Houdijk H, Harlaar J The aim of this study was to assess the functional effects and mechanical contribution of Ankle Foot Orthoses (AFO) prescribed to overcome drop-foot gait. We hypothesized that poor function [...]
Cognitive impairment in multiple sclerosis is associated to different patterns of gray matter atrophy according to clinical phenotype.
28/08/2010 05:37
Related Articles Cognitive impairment in multiple sclerosis is associated to different patterns of gray matter atrophy according to clinical phenotype. Hum Brain Mapp. 2010 Aug 25; Authors: Riccitelli G, Rocca MA, Pagani E, Rodegher ME, Rossi P, Falini A, Comi G, Filippi M Objective: To investigate whether cognitive impairment in multiple sclerosis (MS) patients is associated to different patterns of gray matter (GM) atrophy and T2-visible lesion distribution a [...]
Sonographic basal ganglia alterations are related to non-motor symptoms in multiple sclerosis.
28/08/2010 05:37
Related Articles Sonographic basal ganglia alterations are related to non-motor symptoms in multiple sclerosis. J Neurol. 2010 Aug 26; Authors: Horowski S, Zettl UK, Benecke R, Walter U The anatomical basis of cognitive dysfunction and other non-motor symptoms in multiple sclerosis (MS) is poorly understood. In MS patients, transcranial sonography (TCS) shows neurodegenerative disease-like lesions of the substantia nigra (SN) and basal ganglia, thought to refle [...]
Are somatosensory evoked potentials of the tibial nerve the most sensitive test in diagnosing multiple sclerosis?
28/08/2010 05:37
Related Articles Are somatosensory evoked potentials of the tibial nerve the most sensitive test in diagnosing multiple sclerosis? Neurol India. 2010 Jul-Aug;58(4):537-41 Authors: Djuric S, Djuric V, Zivkovic M, Milosevic V, Jolic M, Stamenovic J, Djordjevic G, Calixto M Background : Multiple sclerosis (MS) is mostly diagnosed clinically, but the diagnosis has significantly improved through the use of brain magnetic resonance imaging (MRI), testing of cerebrosp [...]
Assessment of JC virus DNA in blood and urine from natalizumab-treated patients.
26/08/2010 15:49
Assessment of JC virus DNA in blood and urine from natalizumab-treated patients. Ann Neurol. 2010 Aug 24; Authors: Rudick RA, O'Connor PW, Polman CH, Goodman AD, Ray SS, Griffith NM, Jurgensen SA, Gorelik L, Forrestal F, Sandrock AW, E Goelz S OBJECTIVE: Analyses were conducted to determine the clinical utility of measuring JC virus (JCV) DNA in blood or urine of natalizumab-treated multiple sclerosis (MS) patients to predict the risk of progressive multifocal [...]
Anti-JC virus antibodies: Implications for PML Risk Stratification.
26/08/2010 15:49
Anti-JC virus antibodies: Implications for PML Risk Stratification. Ann Neurol. 2010 Aug 24; Authors: Gorelik L, Lerner M, Bixler S, Crossman M, Schlain B, Simon K, Pace A, Cheung A, Chen LL, Berman M, Zein F, Wilson E, Yednock T, Sandrock A, Goelz SE, Subramanyam M OBJECTIVE: A study was undertaken to establish an enzyme-linked immunosorbent assay (ELISA) to detect JC virus (JCV)-specific antibodies in multiple sclerosis (MS) patients, and to evaluate its pot [...]
Tubulin polymerization promoting protein (TPPP/p25) as a marker for oligodendroglial changes in multiple sclerosis.
26/08/2010 15:49
Tubulin polymerization promoting protein (TPPP/p25) as a marker for oligodendroglial changes in multiple sclerosis. Glia. 2010 Aug 24; Authors: Höftberger R, Fink S, Aboul-Enein F, Botond G, Olah J, Berki T, Ovadi J, Lassmann H, Budka H, Kovacs GG Multiple sclerosis (MS) is an idiopathic chronic inflammatory demyelinating disease of the central nervous system with variable extent of remyelination. Remyelination originates from oligodendrocyte (OG) precursor c [...]
Sphingolipids in Neurodegeneration.
26/08/2010 15:49
Sphingolipids in Neurodegeneration. Neuromolecular Med. 2010 Aug 25; Authors: Haughey NJ Although the brain contains a high content of sphingolipids, we know relatively little about the roles that sphingolipids play in regulating neural functions. Once regarded only for their structural roles in maintaining the integrity of cellular and sub-cellular compartments, it is now apparent that many sphingolipid species are biologically active and play important roles [...]
Ophthalmologic manifestations commonly misdiagnosed as demyelinating events in multiple sclerosis patients.
26/08/2010 15:49
Ophthalmologic manifestations commonly misdiagnosed as demyelinating events in multiple sclerosis patients. Curr Opin Ophthalmol. 2010 Aug 21; Authors: Simao LM PURPOSE OF REVIEW: Multiple sclerosis may affect both afferent and efferent visual pathways, and sometimes physicians err on ordinary ophthalmologic diagnosis due to overlapping symptoms between demyelinating and nondemyelinating visual diseases. The present article highlights nondemyelinating ocular o [...]
Infectious mononucleosis-linked HLA class I single nucleotide polymorphism is associated with multiple sclerosis.
26/08/2010 15:49
Infectious mononucleosis-linked HLA class I single nucleotide polymorphism is associated with multiple sclerosis. Mult Scler. 2010 Aug 24; Authors: Jafari N, Broer L, Hoppenbrouwers IA, van Duijn CM, Hintzen RQ Background: Multiple sclerosis is a presumed autoimmune disease associated with genetic and environmental risk factors such as infectious mononucleosis. Recent research has shown infectious mononucleosis to be associated with a specific HLA class I poly [...]
A method for evaluating treatment switching criteria in multiple sclerosis.
26/08/2010 15:49
A method for evaluating treatment switching criteria in multiple sclerosis. Mult Scler. 2010 Aug 24; Authors: Healy BC, Glanz BI, Stankiewicz J, Buckle G, Weiner H, Chitnis T Background and Objective: We investigated a method to evaluate a treatment switching approach, namely treatment change after one multiple sclerosis (MS) relapse.Methods: Patients who experienced a relapse while on a first-line disease-modifying therapy, glatiramer acetate, were identified [...]
The Dizzy Patient.
26/08/2010 15:49
The Dizzy Patient. Med Clin North Am. 2010 Sep;94(5):989-1002 Authors: Kutz JW The dizzy patient often presents a challenge to the physician. The history is the most important component of the evaluation of the dizzy patient and often allows the cause of the dizziness to be categorized as peripheral or central. Peripheral causes include benign paroxysmal positional vertigo, Meniere's disease, and vestibular neuritis. Central causes include migraine-associated [...]
Characterization of Brain Lesions in a Mouse Model of Progressive Multiple Sclerosis.
26/08/2010 15:49
Characterization of Brain Lesions in a Mouse Model of Progressive Multiple Sclerosis. Exp Neurol. 2010 Aug 21; Authors: Levy H, Assaf Y, Frenkel D Multiple sclerosis (MS) is an autoimmune disease of the central nervous system characterized by damage to the neuronal myelin sheath, which results in different levels of muscle paralysis that can lead to neuronal death. In most MS mouse models, the neurologic damage mostly affects the spinal cord with limited damag [...]
An N-terminally truncated envelope protein encoded by a human endogenous retrovirus W locus on chromosome Xq22.3.
26/08/2010 15:49
An N-terminally truncated envelope protein encoded by a human endogenous retrovirus W locus on chromosome Xq22.3. Retrovirology. 2010 Aug 24;7(1):69 Authors: Roebke C, Wahl S, Laufer G, Stadelmann C, Sauter M, Mueller-Lantzsch N, Mayer J, Ruprecht K ABSTRACT: BACKGROUND: We previously showed that the envelope (env) sequence of a human endogenous retrovirus (HERV)-W locus on chromosome Xq22.3 is transcribed in human peripheral blood mononuclear cells. The env o [...]
Intrathecal Synthesis of Immunoglobulins in Patients with Unexplained Intermediate Uveitis.
26/08/2010 15:49
Intrathecal Synthesis of Immunoglobulins in Patients with Unexplained Intermediate Uveitis. Ocul Immunol Inflamm. 2010 Aug 25; Authors: Roux KL, Kodjikian L, Marignier R, Bancel J, Broussolle C, Sève P Purpose: To assess the value of lumbar punctures in adult patients with unexplained intermediate uveitis (IU). Methods: Retrospective study of 17 patients with unexplained IU. All the patients underwent physical examination, complete laboratory tests, and cereb [...]
[Congenital rhabdomyoma--prenatal diagnosis with three-dimensional ultrasound of two cases with different pregnancy outcome]
26/08/2010 15:49
[Congenital rhabdomyoma--prenatal diagnosis with three-dimensional ultrasound of two cases with different pregnancy outcome] Akush Ginekol (Sofiia). 2010;49(4):59-63 Authors: Congenital rhabdomyoma is the most common benign tumor of the fetal heart. Usually it occurs as a single or multiple lesions located within the ventricles and it is often associated with tuberous sclerosis after birth. We present two cases of congenital rhabdomyoma diagnosed in the third [...]
Management of difficult cases in female urology and neurourology at the Reed M. Nesbit society meeting. Festschrift in honor of Edward J. McGuire, MD.
26/08/2010 15:49
Related Articles Management of difficult cases in female urology and neurourology at the Reed M. Nesbit society meeting. Festschrift in honor of Edward J. McGuire, MD. Neurourol Urodyn. 2010;29 Suppl 1:S2-12 Authors: Blaivas J, McGuire EJ, Stöhrer M, Webster GD, Cameron AP This is a panel discussion of seven complex urologic cases in female urology and neurourology. Differences in diagnosis and management are discussed by this international panel of experts. [...]
The broad impact of MS.
26/08/2010 15:49
Related Articles The broad impact of MS. Eur J Neurol. 2010 Mar;17(3):341 Authors: Halper J PMID: 19922455 [PubMed - indexed for MEDLINE]
Assessing the accuracy of observer-reported ancestry in a biorepository linked to electronic medical records.
25/08/2010 17:21
Related Articles Assessing the accuracy of observer-reported ancestry in a biorepository linked to electronic medical records. Genet Med. 2010 Aug 20; Authors: Dumitrescu L, Ritchie MD, Brown-Gentry K, Pulley JM, Basford M, Denny JC, Oksenberg JR, Roden DM, Haines JL, Crawford DC PURPOSE:: The Vanderbilt DNA Databank (BioVU) is a biorepository that currently contains >80,000 DNA samples linked to electronic medical records. Although BioVU is a valuable sourc [...]
IgG4-related Sclerosing Disease: A Critical Appraisal of an Evolving Clinicopathologic Entity.
25/08/2010 17:21
Related Articles IgG4-related Sclerosing Disease: A Critical Appraisal of an Evolving Clinicopathologic Entity. Adv Anat Pathol. 2010 Sep;17(5):303-32 Authors: Cheuk W, Chan JK An elevated serum titer of immunoglobulin G4 (IgG4), the least common (3% to 6%) of the 4 subclasses of IgG, is a surrogate marker for the recently characterized IgG4-related sclerosing disease. The syndrome affects predominantly middle-aged and elderly patients, with male predominance. [...]
Botulinum toxin improves dysphagia associated with multiple sclerosis.
25/08/2010 17:21
Related Articles Botulinum toxin improves dysphagia associated with multiple sclerosis. Eur J Neurol. 2010 Aug 22; Authors: Restivo DA, Marchese-Ragona R, Patti F, Solaro C, Maimone D, Zappalá G, Pavone A Objective: To evaluate the efficacy of botulinum neurotoxin type A (BoNT/A) for severe oro-pharyngeal dysphagia associated with multiple sclerosis (MS). Patients and methods: BoNT/A was injected percutaneously into the hyperactive cricopharyngeal muscle of 14 [...]
[Quantitative ocular-motor tests analysis in multiple sclerosis]
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Related Articles [Quantitative ocular-motor tests analysis in multiple sclerosis] Otolaryngol Pol. 2010 May-Jun;64(3):147-51 Authors: Józefowicz-Korczyńska M, Durko M, Pajor A Abnormalities in the ocular-motor reflex recorded in electronystagmography may indicate central vestibular system impairment. Multiple sclerosis (MS) is the most common chronic, debilitating disease characterized by focal demyelinization that develops throughout the central nerves syste [...]
Combined effects of smoking, anti-ebna antibodies, and hla-drb1*1501 on multiple sclerosis risk.
25/08/2010 17:21
Related Articles Combined effects of smoking, anti-ebna antibodies, and hla-drb1*1501 on multiple sclerosis risk. Neurology. 2010 Aug 24;75(8):752 Authors: Exley C PMID: 20733153 [PubMed - in process]
Interleukin-15 attenuates transforming growth factor-beta1-induced myofibroblast differentiation in human fetal lung fibroblasts.
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Appearance of Tissue Transglutaminase in Astrocytes in Multiple Sclerosis Lesions: A Role in Cell Adhesion and Migration?
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Related Articles Appearance of Tissue Transglutaminase in Astrocytes in Multiple Sclerosis Lesions: A Role in Cell Adhesion and Migration? Brain Pathol. 2010 Aug 20; Authors: van Strien ME, Drukarch B, Bol JG, van der Valk P, van Horssen J, Gerritsen WH, Breve JJ, van Dam AM Abstract Multiple Sclerosis (MS) is a neuroinflammatory disease mainly affecting young adults. A major pathological hallmark of MS is the presence of demyelinated lesions in the central ner [...]