PeRSSonalized Microbiology on Webicina.Com

New way to improve antibiotic production

Tue, 18 Jun 2013 00:04:04 +0200

An antibiotic has been found to stimulate its own production. The findings, to be published in PNAS, could make it easier to scale up antibiotic production for commercialisation.

BacterioFiles Special Edition - ASM2013 General Meeting Day 3

Tue, 18 Jun 2013 00:02:16 +0200

Here's my summary of the third day of ASM2013, wherein I met with neat people and ideas. {joomp3_ext}http://traffic.libsyn.com/bacteriofiles/BFspecialASM2013-May20.mp3{/joomp3_ext} Download Episode

Mapping Translation Sites in the Human Genome

Mon, 17 Jun 2013 19:13:09 +0200

Because of their central importance to biology, proteins have been the focus of intense research, particularly the manner in which they are produced from genetically coded templates -- a process commonly known as translation. While the gene [...]

Platelets Help Tackle Bacteria

Mon, 17 Jun 2013 19:13:09 +0200

The cell fragments play a role in the body’s first line of defense against bacterial infection, helping white blood cells grab blood-borne bacteria in the liver. Platelets may contribute to protection against bacterial infection, according [...]

Discovery of how a gene that regulates factors involved in bacteria pathogenicity acts

Mon, 17 Jun 2013 19:13:09 +0200

In a piece of work carried out by the Carbohydrate Metabolism Research Team of the Institute of Agrobiotechnology (a centre jointly owned by the NUP/UPNA-Public University of Navarre, the Spanish National Scientific Research Council-CSIC, a [...]

'Chase and Run' Cell Movement Mechanism Explains Process of Metastasis

Mon, 17 Jun 2013 19:13:09 +0200

A mechanism that cells use to group together and move around the body -- called 'chase and run' -- has been described for the first time by scientists at UCL. Published in Nature Cell Biology, the new study focuses on the process that occur [...]

Scientists reconstruct the genome of medieval strains of the pathogen responsible for leprosy

Mon, 17 Jun 2013 19:13:09 +0200

Why was there a sudden drop in the incidence of leprosy at the end of the Middle Ages? To answer this question, biologists and archeologists reconstructed the genomes of medieval strains of the pathogen responsible for the disease, which th [...]

Retrospective, June 2013

Mon, 17 Jun 2013 19:13:09 +0200

We continue our semi-annual ritual and post this quick tour of our blog posts published since December, 2012. Pictures Considered Our new section dealing with “pictures that made a difference but may be nearly forgotten by now” seems to b [...]

Community acquisition of beta-lactamase producing Enterobacteriaceae in neonatal gut

Mon, 17 Jun 2013 18:37:02 +0200

Background: Commensal flora constitutes a reservoir of antibiotic resistance. The increasing variety of beta-lactamases and the emergence of Carbapenem resistant Enterobacteriaceae (CRE) in community, raise concerns regarding efficacy of beta-lactams

Metaproteomic analysis of ratoon sugarcane rhizospheric soil

Mon, 17 Jun 2013 18:37:02 +0200

Background: The current study was undertaken to elucidate the mechanism of yield decline in ratoon sugarcane using soil metaproteomics combined with community level physiological profiles (CLPP) analysis. Results: The available stalk number, stalk di

Arxula adeninivorans xanthine oxidoreductase and its application in the production of food with low purine content

Mon, 17 Jun 2013 18:36:16 +0200

Aims Isolation and characterization of xanthine oxidoreductase and its application in the production of food with low purine content. Methods and Results The A. adeninivorans xanthine oxidoreductase is an inducible enzyme. The best inducers were

Characterization of Tetracycline‐resistant Bacteria in an Urbanizing Subtropical Watershed

Mon, 17 Jun 2013 18:36:16 +0200

Aims The objective of this study was to determine if varying levels of urbanization influence the dominant bacterial species of mildly resistant (0.03 mmol l−1 tetracycline) and highly resistant (0.06 mmol l−1 tetracycline) bacteria in sedimen

Bioaugmentation of chromium polluted soil microcosms with Candida tropicalis diminish phytoavailable chromium

Mon, 17 Jun 2013 18:36:16 +0200

Aim localization of Cr(VI) removal activity in Candida tropicalis strain and the study of its Cr(VI) removal capacity in soil. Methods and Results Candida tropicalis strain HE650140, showed a remarkable capacity to completely reduce 50 mg l−1

Design and Construction of a Single Tube, Quantitative End‐Point, LATE‐PCR Multiplex Assay for Ventilator‐Associated Pneumonia

Mon, 17 Jun 2013 18:36:16 +0200

Aims The goal of this study was to develop a molecular diagnostic multiplex assay for the quantitative detection of microbial pathogens commonly responsible for Ventilator‐ Associated Pneumonia (VAP) and their antibiotic resistance using Linear�

How JC virus causes PML

Mon, 17 Jun 2013 18:21:02 +0200

JC polyomavirus is a bit of a mystery. Many people are infected with it, but few become ill as a result. This virus bides its time.The post How JC virus causes PML appeared first on MicrobiologyBytes.

New edition of the USP

Mon, 17 Jun 2013 18:21:02 +0200

A new edition of the USP has recently been issued: USP36-NF31. The changes of interest are: General Chapters Listed are items in which changes have been made to existing official text. General Tests and Assays Chapter 1 & [...]

Retrospective, June 2013

Mon, 17 Jun 2013 13:35:05 +0200

ADVANCE Reading of the Day: Sylvia Earle, Women in Japan and the Gulf, Spaceflight

Mon, 17 Jun 2013 05:29:02 +0200

How Open Are You? Part 1: Metrics to Measure Openness and Free Availability of Publications

Mon, 17 Jun 2013 00:37:02 +0200

'Chase and run' cell movement mechanism explains process of metastasis

Sun, 16 Jun 2013 19:29:03 +0200

A mechanism that cells use to group together and move around the body – called 'chase and run' - has been described for the first time by scientists at UCL.

TWiV 237: Paleovirology with Michael Emerman

Sun, 16 Jun 2013 19:27:08 +0200

{joomp3_ext}http://traffic.libsyn.com/twiv/TWiV237.mp3{/joomp3_ext} Hosts: Vincent Racaniello and Rich Condit

ATCC Bacteriology Culture Guide

Sun, 16 Jun 2013 18:41:03 +0200

The American Type Culture Collection (ATCC) have produced a useful guide containing general technical information regarding bacterial growth, propagation, preservation, and application. The guide is available to those who register on [...]

Ex vivo porcine vaginal mucosal model of infection for determining effectiveness and toxicity of antiseptics

Sun, 16 Jun 2013 17:55:14 +0200

Aims To develop a semi‐high through‐put ex vivo mucosal model for determining efficacy and toxicity of antiseptics. Methods and Results Explants (5mm) from freshly excised, porcine vaginal mucosa were infected with methicillin sensitive Staph

The role of the RNA chaperone Hfq in Haemophilus influenzae pathogenesis

Sun, 16 Jun 2013 03:11:02 +0200

Background: The RNA binding protein Hfq of Haemophilus influenzae is highly homologous to Hfq from other bacterial species. In many of these other bacteria, Hfq affects the expression of a broad range of genes and enhances the ability to respond to s

TWiP 55 letters

Sat, 15 Jun 2013 19:45:08 +0200

Jessie writes: Hi Vince and Dick! Has anyone volunteered to do transcripts for TWIP? I love this show, and I'd love to be able to contribute in some way. Forgive me if transcripts already exist and I'm just not finding them on the website. [...]

TWiP 55: A ladybird's weapon

Sat, 15 Jun 2013 19:45:08 +0200

{joomp3_ext}http://traffic.libsyn.com/twip/TWiP055.mp3{/joomp3_ext} Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson reveal...

Antibiotic Resistance Using Crystallography

Sat, 15 Jun 2013 19:11:03 +0200

Scientists at the University of Bristol, together with collaborators at the University of Aveiro, Portugal, have solved the structure of an enzyme that breaks down carbapenems , antibiotics 'of last resort' which, until recently, were [...]

Researchers unearth bioenergy potential in leaf-cutter ant communities

Sat, 15 Jun 2013 00:04:04 +0200

As spring warms up Wisconsin, humans aren't the only ones tending their gardens. At the University of Wisconsin–Madison Department of Bacteriology, colonies of leaf-cutter ants cultivate thriving communities of fungi and bacteria using fres [...]

Nasty toxin helps E. coli survive in water

Fri, 14 Jun 2013 19:10:09 +0200

Strains of E. coli that produce the Shiga toxin last longer in lake water. The toxin appears to help E. coli fend off predators. “The take-home lesson is that E. coli that produce Shiga toxin persisted longer in recreational water than E. c [...]

Pharmaceutical Water Guideline (WHO)

Fri, 14 Jun 2013 19:05:34 +0200

An update from the European Compliance Academy on the revised WHO standard for pharmaceutical water. The current TRS 970 of the WHO comprises an updated version of the guideline regarding the manufacture and distribution of water fo [...]

Extreme virus resistance in plants

Fri, 14 Jun 2013 19:05:33 +0200

When a virus infects a plant, a slient war rages, fought with RNA weapons. The post Extreme virus resistance in plants appeared first on MicrobiologyBytes.

Adaptive mechanisms of Campylobacter jejuni to erythromycin treatment

Fri, 14 Jun 2013 16:08:02 +0200

Background: Macrolide is the drug of choice to treat human campylobacteriosis, but Campylobacter resistance to this antibiotic is rising. The mechanisms employed by Campylobacter jejuni to adapt to erythromycin treatment remain unknown and are examin

Another week - another microbial art project

Fri, 14 Jun 2013 10:53:03 +0200

ADVANCE Journal Club: Developing Graduate Students of Color for the Professoriate in STEM

Fri, 14 Jun 2013 01:24:02 +0200

Dangerous strains of E. coli may linger longer in water than benign counterparts, study finds

Fri, 14 Jun 2013 00:07:05 +0200

A toxin dangerous to humans may help E. coli fend off aquatic predators, enabling strains of E. coli that produce the toxin to survive longer in lake water than benign counterparts, a new study finds.

Overview of Polyketides and Polyketide Biosynthesis

Thu, 13 Jun 2013 23:28:02 +0200

Overview of Polyketides and Polyketide Biosynthesis An overview of polyketides and their biosynthesis. This is a seminar by Prof. Chaitan Khosla (Stanford University), May 2007. Available under a Creative Comm... From: César S&aac [...]

El neumococo fratricida (The pneumococcal fratricide)

Thu, 13 Jun 2013 23:28:02 +0200

El neumococo fratricida (The pneumococcal fratricide) Includes English subtitles *** El neumococo, una bacteria que causa graves enfermedades en el ser humano, mata a sus propios hermanos para incrementar la... From: César S&aacut [...]

Inner Structure of an Eukaryotic Cell

Thu, 13 Jun 2013 23:28:02 +0200

Inner Structure of an Eukaryotic Cell Electron cryotomographic reconstruction of an Ostreococcus tauri cell (a photosynthetic eukaryote). The three-dimensional reconstruction of a single cell is ... From: César Sánchez View [...]

Virus receptors and the host-virus arms race

Thu, 13 Jun 2013 14:38:08 +0200

A nice short article looking at pathogen-host co-evolution.The post Virus receptors and the host-virus arms race appeared first on MicrobiologyBytes.

Pharmeuropa 25.2

Thu, 13 Jun 2013 14:38:08 +0200

A new edition of Pharmeuropa: 25.2, has recently been published. This is the forum where draft European Pharmacopeia monographs are published for public comment. If no further revision is required the draft monograph is proposed to the [...]

Fine Reading: The gut microbiota of insects – diversity in structure and function

Thu, 13 Jun 2013 14:38:02 +0200

Novel Coronavirus (MERS)