PeRSSonalized High Blood Pressure on Webicina.Com

High Heart Rate in Pregnancy Is Modulated by Augmented Expression of an Ion Channel, HCN-2, in Pacemaker Tissue [Editorials]

Tue, 21 May 2013 02:36:04 +0200

Blinding the Monocytes to Protect the Heart [Editorials]

Tue, 21 May 2013 02:36:04 +0200

Upregulation of the Hyperpolarization-Activated Current Increases Pacemaker Activity of the Sinoatrial Node and Heart Rate During Pregnancy in Mice [Arrhythmia/Electrophysiology]

Tue, 21 May 2013 02:36:04 +0200

Background— Pregnancy is associated with a faster heart rate (HR), which is a risk factor for arrhythmias. However, the underlying mechanisms for this increased HR are poorly understood. Therefore, this study was performed to gain mechanistic

Safety of Sports for Athletes With Implantable Cardioverter-Defibrillators: Results of a Prospective, Multinational Registry [Arrhythmia/Electrophysiology]

Tue, 21 May 2013 02:36:04 +0200

Background— The risks of sports participation for implantable cardioverter-defibrillator (ICD) patients are unknown. Methods and Results— Athletes with ICDs (age, 10–60 years) participating in organized (n=328) or high-risk (n=44)

Population-Based Study of Incidence and Outcome of Acute Aortic Dissection and Premorbid Risk Factor Control: 10-Year Results From the Oxford Vascular Study [Epidemiology and Prevention]

Tue, 21 May 2013 02:36:04 +0200

Background— Acute aortic dissection is a preventable life-threatening condition. However, there have been no prospective population-based studies of incidence or outcome to inform an understanding of risk factors, strategies for prevention, or

Monocyte-Directed RNAi Targeting CCR2 Improves Infarct Healing in Atherosclerosis-Prone Mice [Heart Failure]

Tue, 21 May 2013 02:36:04 +0200

Background— Exaggerated and prolonged inflammation after myocardial infarction (MI) accelerates left ventricular remodeling. Inflammatory pathways may present a therapeutic target to prevent post-MI heart failure. However, the appropriate magn

Mechanisms of Tissue Uptake and Retention in Zotarolimus-Coated Balloon Therapy [Interventional Cardiology]

Tue, 21 May 2013 02:36:04 +0200

Background— Drug-coated balloons are increasingly used for peripheral vascular disease, and, yet, mechanisms of tissue uptake and retention remain poorly characterized. Most systems to date have used paclitaxel, touting its propensity to assoc

Endocarditis in Adults With Bacterial Meningitis [Valvular Heart Disease]

Tue, 21 May 2013 02:36:04 +0200

Background— Endocarditis may precede or complicate bacterial meningitis, but the incidence and impact of endocarditis in bacterial meningitis are unknown. Methods and Results— We assessed the incidence and clinical characteristics of pa

Coronary Artery Stenosis in Moyamoya Disease: Tissue Characterization by 256-Slice Multi-Detector CT and Virtual Histology [Images in Cardiovascular Medicine]

Tue, 21 May 2013 02:36:04 +0200

Transforming Cardiovascular Health Through Genes and Environment: Presidential Address at the American Heart Association 2012 Scientific Sessions [Special Report]

Tue, 21 May 2013 02:36:04 +0200

Abstracts From the Emerging Science Series, April 24, 2013 [Abstracts From the Emerging Science Series]

Tue, 21 May 2013 02:36:04 +0200

Maternal Cardiovascular Risk Profile After Placental Abruption [Pregnancy]

Thu, 16 May 2013 10:21:05 +0200

The prevalence of premature cardiovascular diseases (CVD) is increased in women with a history of maternal placental syndromes, including pregnancy-associated hypertensive disorders (eg, preeclampsia), fetal growth restriction, and placental abrupti

Blood Pressure in Treated Hypertensive Individuals With the MTHFR 677TT Genotype Is Responsive to Intervention With Riboflavin: Findings of a Targeted Randomized Trial [Stratified Treatment of Hypertension]

Thu, 16 May 2013 10:21:05 +0200

Intervention with riboflavin was recently shown to produce genotype-specific lowering of blood pressure (BP) in patients with premature cardiovascular disease homozygous for the 677C->T polymorphism (TT genotype) in the gene encoding the enzyme m

Intensive Blood Pressure Lowering Increases Cerebral Blood Flow in Older Subjects With Hypertension [Blood Pressure Lowering and Cerebral Blood Flow]

Thu, 16 May 2013 10:21:05 +0200

Hypertension is associated with reduced cerebral blood flow (CBF). Intensive (<130/80 mm Hg) blood pressure (BP) lowering in older people might give greater reduction in cardiovascular risk, but there are concerns that this might produce hypoperf

Role of T Regulatory Lymphocytes in the Pathogenesis of High-Fructose Diet-Induced Metabolic Syndrome [Metabolic Syndrome]

Thu, 16 May 2013 10:21:05 +0200

We recently showed that T regulatory lymphocytes (Treg), which are immune suppressors of inflammatory responses, play a role blunting the development of hypertension-induced injury. Treg are unchanged or decreased in children with metabolic syndrome

Body Fat Is Associated With Reduced Aortic Stiffness Until Middle Age [Obesity]

Thu, 16 May 2013 10:21:05 +0200

Obesity is a major risk factor for cardiometabolic disease, but the effect of body composition on vascular aging and arterial stiffness remains uncertain. We investigated relationships among body composition, blood pressure, age, and aortic pulse wa

Chronic Knockdown of the Nucleus of the Solitary Tract AT1 Receptors Increases Blood Inflammatory-Endothelial Progenitor Cell Ratio and Exacerbates Hypertension in the Spontaneously Hypertensive Rat [Inflammation and Hypertension]

Thu, 16 May 2013 10:21:05 +0200

AT1 receptor subtype a (AT1Ra) expression is increased in the nucleus of the solitary tract (NTS) in spontaneously hypertensive rat (SHR) compared with Wistar Kyoto controls. However, the chronic role of AT1Ra in the NTS for cardiovascular control i

Renal Responses to Long-Term Carotid Baroreflex Activation Therapy in Patients With Drug-Resistant Hypertension [Renal Response to Baroreflex Activation Therapy]

Thu, 16 May 2013 10:21:05 +0200

Carotid baroreflex activation has been demonstrated to provide enduring reductions in arterial blood pressure. The aim of this study was to investigate the effect of long-term therapy on renal function. A total of 322 patients were enrolled in the R

Central Pulse Pressure Is an Independent Determinant of Vascular Remodeling in the Retinal Circulation [Retinal Vessels]

Thu, 16 May 2013 10:21:05 +0200

Pulse pressure has been recognized as a risk factor for stroke. Moreover, it was shown that central pulse pressure relates more strongly to vascular disease and outcome than (peripheral) brachial pulse pressure. Because vascular remodeling in the re

White Coat Hypertension Is More Risky Than Prehypertension: Important Role of Arterial Wave Reflections [White Coat Hypertension]

Thu, 16 May 2013 10:21:05 +0200

Arterial aging may link cardiovascular risk to white coat hypertension (WCH). The aims of the present study were to investigate the role of arterial aging in the white coat effect, defined as the difference between office and 24-hour ambulatory syst

High Blood Pressure and Cerebral White Matter Lesion Progression in the General Population [White Matter Lesions]

Thu, 16 May 2013 10:21:05 +0200

High blood pressure is considered an important risk factor for cerebral white matter lesions (WMLs) in the aging population. In a longitudinal population-based study of 665 nondemented persons, we investigated the longitudinal relationship of systol

Beyond Medications and Diet: Alternative Approaches to Lowering Blood Pressure: A Scientific Statement From the American Heart Association [AHA Scientific Statement]

Thu, 16 May 2013 10:21:05 +0200

Many antihypertensive medications and lifestyle changes are proven to reduce blood pressure. Over the past few decades, numerous additional modalities have been evaluated in regard to their potential blood pressure–lowering abilities. However,

Assessment of oxidative status markers and NO bioavailability in hypertensive disorders of pregnancy